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A New Approach in the Treatment of Type 2 Diabetes Mellitus: Intermittent Fasting Diets

Year 2024, Volume: 9 Issue: 1, 83 - 86, 30.04.2024
https://doi.org/10.51754/cusbed.1342655

Abstract

Type 2 diabetes is an important metabolic disease characterized by hyperglycemia, which causes many complications associated with long-term morbidity and mortality risk. The aim of type 2 diabetes treatment is to prevent or delay the complications of diabetes and also to improve the patient's quality of life. The prevalence of type 2 diabetes is increasing exponentially and a high prevalence rate is observed in both developed and underdeveloped countries. Therefore, new strategies come to the fore in the treatment and prevention of type 2 diabetes. Recent studies have shown that intermittent fasting diets have beneficial effects in patients with type 2 diabetes. However, it should not be forgotten that these diet methods have some risks and it should be emphasized that intermittent fasting diets should be evaluated individually in patients with diabetes.

References

  • Albosta, M., & Bakke, J. (2021). Intermittent fasting: is there a role in the treatment of diabetes? A review of the literature and guide for primary care physicians. Clin Diabetes Endocrinol, 7(1), 3.
  • Beli, E., Yan, Y., Moldovan, L., et al. (2018). Restructuring of the gut microbiome by intermittent fasting prevents retinopathy and prolongs survival in db/db mice. Diabetes, 67, 1867-1879.
  • Borgundvaag, E., Mak, J., & Kramer, C.K. (2021) Metabolic Impact of Intermittent Fasting in Patients With Type 2 Diabetes Mellitus: A Systematic Review and Meta-analysis of Interventional Studies. J Clin Endocrinol Metab, 106(3), 902-911.
  • Carter, S., Clifton, P.M., & Keogh, J.B. (2018). Effect of intermittent compared with continuous energy restricted diet on glycemic control in patients with type 2 diabetes: a randomized noninferiority trial. JAMA Netw Open, 1(3), 180756.
  • Cho, Y., Hong, N., & Kim, K.W., et al. (2019). The Effectiveness of Intermittent Fasting to Reduce Body Mass Index and Glucose Metabolism: A Systematic Review and Meta-Analysis. J Clin Med, 8(10), 1645.
  • Corley, B.T., Carroll, R.W., Hall, R.M., Weatherall, M., Parry-Strong, A., & Krebs. J.D. (2018). Intermittent fasting in type 2 diabetes mellitus and the risk of hypoglycaemia: a randomized controlled trial. Diabet Med, 35(5), 588-594.
  • Federation ID. IDF diabetes atlas ninth. Dunia: IDF. (2021).
  • Durruty P., Sanzana M., Sanhueza L. (2019). Pathogenesis of Type 2 Diabetes Mellitus. Type 2 Diabetes: IntechOpen.
  • Grajower, M.M., & Horne, B.D. (2019): Clinical management of intermittent fasting in patients with diabetes mellitus . Nutrients, 11, 873.
  • Haluzík, M., & Mráz, M. (2018). Intermittent Fasting and Prevention of Diabetic Retinopathy: Where Do We Go From Here? Diabetes, 67(9), 1745-1747.
  • Kahn, C.R. (1985). The molecular mechanism of insulin action. Annu Rev Med, 36, 429-51.
  • Laakso, M. (2019). Biomarkers for type 2 diabetes. Mol Metab, 27, 139-146.
  • López-Jaramillo, P., Gómez-Arbeláez, D., & López-López, J., et al. (2014). The role of leptin/adiponectin ratio in metabolic syndrome and diabetes. Horm Mol Biol Clin Investig, 18(1), 37-45.
  • Minokoshi, Y., Toda, C., & Okamoto, S. (2012). Regulatory role of leptin in glucose and lipid metabolism in skeletal muscle. Indian J Endocrinol Metab, 16(3), 562-8.
  • Ojo, T.K., Joshua, O.O., Ogedegbe, O.J., Oluwole, O., Ademidun, A., & Jesuyajolu, D. (2022). Role of Intermittent Fasting in the Management of Prediabetes and Type 2 Diabetes Mellitus. Cureus, 14(9), e28800.
  • Petersen, M.C., & Shulman, G.I. (2018). Mechanisms of insulin action and insulin resistance. Physiol Rev, 98(4), e2133–223.
  • Powers, A.C., Stafford, J.M., & Rickels, M.R. Diabetes mellitus: complications. In: Jameson JL, Fauci AS, Kasper DL, Hauser (2018). SL, Longo DL, Loscalzo J, editors. Harrison's principles of internal medicine, 20e. New York: McGraw-Hill Education.
  • Rajpal, A., & Ismail-Beigi, F. (2020). Intermittent fasting and 'metabolic switch': Effects on metabolic syndrome, prediabetes and type 2 diabetes. Diabetes Obes Metab, 9, 1496-1510.
  • Sami, W., Ansari, T., Butt, N.S., & Ab Hamid, M.R. (2017). Effect of diet on type 2 diabetes mellitus: A review. International journal of health sciences, 11(2), 65.
  • Sanvictores, T., Casale, J., & Huecker, M.R. (2022): Physiology, fasting. StatPearls [Internet]. StatPearls Publishing, Treasure Island, FL.
  • Sutton, E.F., Beyl, R., Early, K.S., Cefalu, W.T., Ravussin, E., & Peterson, C.M. (2018). Early time-restricted feeding improves insulin sensitivity, blood pressure, and oxidative stress even without weight loss in men with prediabetes. Cell Metabolism, 27(6), 1212-21.
  • Tinsley, G.M., & La Bounty, P.M. (2015). Effects of intermittent fasting on body composition and clinical health markers in humans. Nutr Rev, 73(10), 661-674.
  • Vasim, I., Majeed, C.N., & DeBoer, M.D. (2022). Intermittent Fasting and Metabolic Health. Nutrients, 14(3), 631.
  • Wu, Y., Ding, Y., Tanaka, Y., & Zhang, W. (2014). Risk factors contributing to type 2 diabetes and recent advances in the treatment and prevention. Int J Med Sci, 11(11), 1185-200.

Tip 2 Diyabetes Mellitus Tedavisinde Yeni Bir Yaklaşım: Aralıklı Açlık Diyetleri

Year 2024, Volume: 9 Issue: 1, 83 - 86, 30.04.2024
https://doi.org/10.51754/cusbed.1342655

Abstract

Tip 2 diyabet, uzun vadeli morbidite ve mortalite riskli ile ilişkili çok sayıda komplikasyona neden olan hiperglisemi ile karakterize metabolik önemli bir hastalıktır. Tip 2 diyabet tedavisinin amacı, diyabetin komplikasyonlarını önlemek veya geciktirmek olup aynı zamanda hastanın yaşam kalitesini artırmaktır. Tip 2 diyabet prevalansı katlanarak artmakta olup hem gelişmiş hem de gelişmemiş olan ülkelerde yüksek bir prevalans oranı gözlenmektedir. Bu nedenle tip 2 diyabetin tedavisi ve önlenmesinde yeni stratejiler öne çıkmaktadır. Son yıllarda yapılan çalışmalarda aralıklı açlık diyetlerinin tip 2 diyabetli hastalarda yararlı etkiler gösterdiği ortaya konmuştur. Ancak bu diyet yöntemlerinin bazı riskleri olduğu unutulmamalı ve diyabetli hastalarda aralıklı açlık diyetlerinin bireysel olarak değerlendirilmesi gerektiği vurgulanmalıdır.

References

  • Albosta, M., & Bakke, J. (2021). Intermittent fasting: is there a role in the treatment of diabetes? A review of the literature and guide for primary care physicians. Clin Diabetes Endocrinol, 7(1), 3.
  • Beli, E., Yan, Y., Moldovan, L., et al. (2018). Restructuring of the gut microbiome by intermittent fasting prevents retinopathy and prolongs survival in db/db mice. Diabetes, 67, 1867-1879.
  • Borgundvaag, E., Mak, J., & Kramer, C.K. (2021) Metabolic Impact of Intermittent Fasting in Patients With Type 2 Diabetes Mellitus: A Systematic Review and Meta-analysis of Interventional Studies. J Clin Endocrinol Metab, 106(3), 902-911.
  • Carter, S., Clifton, P.M., & Keogh, J.B. (2018). Effect of intermittent compared with continuous energy restricted diet on glycemic control in patients with type 2 diabetes: a randomized noninferiority trial. JAMA Netw Open, 1(3), 180756.
  • Cho, Y., Hong, N., & Kim, K.W., et al. (2019). The Effectiveness of Intermittent Fasting to Reduce Body Mass Index and Glucose Metabolism: A Systematic Review and Meta-Analysis. J Clin Med, 8(10), 1645.
  • Corley, B.T., Carroll, R.W., Hall, R.M., Weatherall, M., Parry-Strong, A., & Krebs. J.D. (2018). Intermittent fasting in type 2 diabetes mellitus and the risk of hypoglycaemia: a randomized controlled trial. Diabet Med, 35(5), 588-594.
  • Federation ID. IDF diabetes atlas ninth. Dunia: IDF. (2021).
  • Durruty P., Sanzana M., Sanhueza L. (2019). Pathogenesis of Type 2 Diabetes Mellitus. Type 2 Diabetes: IntechOpen.
  • Grajower, M.M., & Horne, B.D. (2019): Clinical management of intermittent fasting in patients with diabetes mellitus . Nutrients, 11, 873.
  • Haluzík, M., & Mráz, M. (2018). Intermittent Fasting and Prevention of Diabetic Retinopathy: Where Do We Go From Here? Diabetes, 67(9), 1745-1747.
  • Kahn, C.R. (1985). The molecular mechanism of insulin action. Annu Rev Med, 36, 429-51.
  • Laakso, M. (2019). Biomarkers for type 2 diabetes. Mol Metab, 27, 139-146.
  • López-Jaramillo, P., Gómez-Arbeláez, D., & López-López, J., et al. (2014). The role of leptin/adiponectin ratio in metabolic syndrome and diabetes. Horm Mol Biol Clin Investig, 18(1), 37-45.
  • Minokoshi, Y., Toda, C., & Okamoto, S. (2012). Regulatory role of leptin in glucose and lipid metabolism in skeletal muscle. Indian J Endocrinol Metab, 16(3), 562-8.
  • Ojo, T.K., Joshua, O.O., Ogedegbe, O.J., Oluwole, O., Ademidun, A., & Jesuyajolu, D. (2022). Role of Intermittent Fasting in the Management of Prediabetes and Type 2 Diabetes Mellitus. Cureus, 14(9), e28800.
  • Petersen, M.C., & Shulman, G.I. (2018). Mechanisms of insulin action and insulin resistance. Physiol Rev, 98(4), e2133–223.
  • Powers, A.C., Stafford, J.M., & Rickels, M.R. Diabetes mellitus: complications. In: Jameson JL, Fauci AS, Kasper DL, Hauser (2018). SL, Longo DL, Loscalzo J, editors. Harrison's principles of internal medicine, 20e. New York: McGraw-Hill Education.
  • Rajpal, A., & Ismail-Beigi, F. (2020). Intermittent fasting and 'metabolic switch': Effects on metabolic syndrome, prediabetes and type 2 diabetes. Diabetes Obes Metab, 9, 1496-1510.
  • Sami, W., Ansari, T., Butt, N.S., & Ab Hamid, M.R. (2017). Effect of diet on type 2 diabetes mellitus: A review. International journal of health sciences, 11(2), 65.
  • Sanvictores, T., Casale, J., & Huecker, M.R. (2022): Physiology, fasting. StatPearls [Internet]. StatPearls Publishing, Treasure Island, FL.
  • Sutton, E.F., Beyl, R., Early, K.S., Cefalu, W.T., Ravussin, E., & Peterson, C.M. (2018). Early time-restricted feeding improves insulin sensitivity, blood pressure, and oxidative stress even without weight loss in men with prediabetes. Cell Metabolism, 27(6), 1212-21.
  • Tinsley, G.M., & La Bounty, P.M. (2015). Effects of intermittent fasting on body composition and clinical health markers in humans. Nutr Rev, 73(10), 661-674.
  • Vasim, I., Majeed, C.N., & DeBoer, M.D. (2022). Intermittent Fasting and Metabolic Health. Nutrients, 14(3), 631.
  • Wu, Y., Ding, Y., Tanaka, Y., & Zhang, W. (2014). Risk factors contributing to type 2 diabetes and recent advances in the treatment and prevention. Int J Med Sci, 11(11), 1185-200.
There are 24 citations in total.

Details

Primary Language Turkish
Subjects Nutritional Science, Clinical Nutrition
Journal Section Review
Authors

Merve Soy 0009-0005-9685-6501

Emine Merve Ekici 0000-0001-5409-6309

Early Pub Date April 29, 2024
Publication Date April 30, 2024
Published in Issue Year 2024Volume: 9 Issue: 1

Cite

APA Soy, M., & Ekici, E. M. (2024). Tip 2 Diyabetes Mellitus Tedavisinde Yeni Bir Yaklaşım: Aralıklı Açlık Diyetleri. Cumhuriyet Üniversitesi Sağlık Bilimleri Enstitüsü Dergisi, 9(1), 83-86. https://doi.org/10.51754/cusbed.1342655

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