Abstract
Amaç: Bu çalışmanın amacı polikliniğe başvuran gebelerin uyku apnesi riski ve uyku kalitesi açısından değerlendirilmesidir.
Gereç ve Yöntem: Hastanenin Kadın Hastalıkları ve Doğum Polikliniği'nde Ocak 2016-Ocak 2017 tarihleri arasında yapılan retrospektif tanımlayıcı çalışmaya 31 kadın dahil edildi. Hastaların demografik özellikleri, uyku anket sonuçları, solunum fonksiyon testi değerleri ve doğum bilgileri 8. hafta ve son trimester için geriye dönük olarak elde edildi.
Bulgular: Ortalama uyku süresi 8. haftada 7.9±1.3 saat ve son trimesterde 7.3±2.0 saat idi; iki periyotta anlamlı fark yoktu (p=0.077). Uyku anketlerine göre 8. hafta ile son trimester arasında Stanford Uykululuk Skalası skoru (p=0.047) dışında istatistiksel olarak anlamlı fark yoktu (p>0.05). 8. hafta ile son trimester arasında solunum fonksiyon testi değerleri bakımından anlamlı fark yoktu (p>0.05), iki dönem arasında sadece FEV1 açısından istatistiksel fark vardı (p=0.047). Uyku kalitesi kötü olan 13 gebenin bebeklerinin ortalama doğum ağırlıkları ile uyku kalitesi iyi olan 18 gebenin bebeklerinin ortalama doğum ağırlıkları arasında anlamlı fark bulunmadı (p=0.565).
Sonuç: Sonuç olarak, çalışmamızda Pittsburg Uyku Kalitesi İndeksi'ne göre son trimesterde gebelerin yaklaşık yarısının uyku kalitesi bozulurken, uyku kalitesi kötü olan gebelerde doğum ağırlığı etkilenmedi. Uyku kalitesi, gebelikte OUAS varlığı, gebelik ve doğum sonu komplikasyonlarla ilişkisi net değildir, özellikle komplike gebeliklerde OUAS gebelik çalışmaları yapılmalıdır.
Keywords
References
- 1. Facco FL, Parker CB, Reddy UM, Silver RM, Koch MA, Louis JM et al. Association Between Sleep-Disordered Breathing and Hypertensive Disorders of Pregnancy and Gestational Diabetes Mellitus. Obstet Gynecol 2017;129(1):31-41. doi: 10.1097/AOG.0000000000001805.
- 2. Dominguez JE, Krystal AD, Habib AS. Obstructive Sleep Apnea in Pregnant Women: A Review of Pregnancy Outcomes and an Approach to Management. Anesth Analg 2018;127(5):1167-77. doi: 10.1213/ANE.0000000000003335.
- 3. Louis J, Auckley D, Miladinovic B, Shepherd A, Mencin P, Kumar D et al. Perinatal outcomes associated with obstructive sleep apnea in obese pregnant women. Obstet Gynecol 2012;120(5):1085-92. doi: 10.1097/AOG.0b013e31826eb9d8.
- 4. Ursavaş A, Karadağ M. Sleep breathing disorders in pregnancy. Tuberk Toraks 2009;57(2):237-43.
- 5. Kır Şahin F, Köken G, Coşar E, Saylan F, Fidan F, Yılmazer M et al. Gebelikte uyku apne sendromu ve eşlik eden hastalıklar. Turk J Obstet Gynecol 2008;5(1):22- 7.
- 6. Miskovic A, Simpson M, Dominguez JE, Bullough AS. Recognising obstructive sleep apnoea in pregnancy - a survey of UK obstetric anaesthetists. Anaesthesia 2017;72(12):1564. doi: 10.1111/anae.14151.
- 7. Türk Toraks Derneği Obstrüktif Uyku Apne Sendromu Tanı ve Tedavi Uzlaşı Raporu. Ed: Kılınç O, Bayram H. Turk Thorac J 2012; 13 Suppl.1:30-2.
- 8. Izci B, Ardic S, Firat H, Sahin A, Altinors M, Karacan I. Reliability and validity studies of the Turkish version of the Epworth Sleepiness Scale. Sleep Breath 2008;12(2):161-8.
- 9. Abrishami A, Khajehdehi A, Chung F. A systematic review of screening questionnaires for obstructive sleep apnea. Can J Anaesth 2010;57:423-38.
- 10. MacLean AW, Fekken GC, Saskin P, Knowles JB. Psychometric evaluation of the Stanford Sleepiness Scale. J Sleep Res 1992;1:35-9.
- 11. Abrishami A, Khajehdehi A, Chung F. A systematic review of screening questionnaires for obstructive sleep apnea. Can J Anaesth 2010;57:423-38.
- 12. Hutchison BL, Stone PR, McCowan LM, Stewart AW, Thompson JM, Mitchell EA. BMC Pregnancy Childbirth 2012;10(12):144. doi: 10.1186/1471-2393-12-144.
- 13. Ursavas A, Karadag M, Nalci N, Ercan I, Gozu RO. Self-reported snoring, maternal obesity and neck circumference as risk factors for pregnancy-induced hypertension and preeclampsia. Respiration 2008;76(1):33-9.
- 14. Kabil Kucur S, Kucur C, Seven A, Yüksel B, Gözükara İ, Polat M et al. Gebelikte Uyku Apne Sıklığının Değerlendirilmesi. The Journal of Gynocology-Obstetrics and Neonatalogy 2015;12(5):179-82.
- 15. Başoğlu ÖK, Yürekli BS, Taşkıranlar P, Tunçel Ş, Yılmaz C. Ege Obez Hasta Okulu anket çalışması: obezite ile obstrüktif uyku apne sendromu semptomları ve gündüz uykululuk ilişkisi. Ege Journal of Medicine 2011;50(2):111-7.
- 16. Mindell JA, Cook RA, Nikolovski J. Sleep patterns and sleep disturbances across pregnancy. Sleep Med 2015;16(4):483-8. doi: 10.1016/j.sleep.2014.12.006.
- 17. Louis JM, Koch MA, Reddy UM, Silver RM, Parker CB, Facco FL et al. Predictors of sleep-disordered breathing in pregnancy. Am J Obstet Gynecol. 2018;218(5):521.
- 18. Pien GW, Pack AI, Jackson N, Maislin G, Macones GA, Schwab RJ. Risk factors for sleep-disordered breathing in pregnancy. Thorax 2014;69(4):371-7. doi: 10.1136/thoraxjnl-2012-202718.
- 19. Louis JM, Mogos MF, Salemi JL, Redline S, Salihu HM. Obstructive sleep apnea and severe maternal-infant morbidity/mortality in the United States, 1998-2009. Sleep 2014;37(5):843-9. doi: 10.5665/sleep.3644.
- 20. Tantrakul V, Sirijanchune P, Panburana P, Pengjam J, Suwansathit W, Boonsarngsul V et al. Screening of obstructive sleep apnea during pregnancy: differences in predictive values of questionnaires across trimesters. J Clin Sleep Med 2015;11(2):157-63. doi: 10.5664/jcsm.4464.
- 21. Celik F, Kose M. Gebelikte uyku kalitesinin trimester ile ilişkisi. Kocatepe Tıp Derg 2017;18(3):85-88.
- 22. Şahin Köybaşı E, Yeşiltepe Oskay Ü. Gebelik sürecinin uyku kalitesine etkisi. Gülhane Tıp Derg 2017;59:1-5.
- 23. Kahyaoglu Sut H, Asci O, Topac N. Sleep quality and health-related quality of life in pregnancy. J Perinat Neonat Nurs 2016;30(4):302-9.
- 24. Çoban A, Yanıkkerem UE. Gebelerde uyku kalitesi ve yorgunluk düzeyi. Ege Tıp Dergisi 2010;49(2):87-94.
- 25. Sharma SK, Nehra A, Sinha S, Soneja M, Sunesh K, Sreenivas V et al. Sleep disorders in pregnancy and their association with pregnancy outcomes: a prospective observational study. Sleep Breath 2016;20(1):87-93. doi: 10.1007/s11325-015-1188-9.
- 26. Grindheim G, Toska K, Estensen ME, Rosseland LA. Changes in pulmonary function during pregnancy: a longitudinal cohort study. BJOG. 2012;119(1):94-101. doi: 10.1111/j.1471-0528.2011.03158.x.
Abstract
Aim: The aim of this study is to evaluate pregnant women admitted to the outpatient clinic in terms of sleep apnea risk and sleep quality.
Materials and Method: 31 women were included in this retrospective descriptive study which were conducted at Obstetrics and Gynecology Outpatient Clinic of the Hospital, between January 2016 and January 2017. Demographic characteristics, results of sleep questionnaires, pulmonary function test values, and information about delivery of the patients were obtained retrospectively for the 8th week and last trimester.
Results: The mean sleep time was 7.9±1.3 hours at 8th week and 7.3±2.0 hours at last trimester; with no significant difference in two periods (p=0.077). According to sleep questionnaires there was no statistically significant difference between 8th week and the last trimester (p>0.05), except Stanford Sleepiness Scale score (p=0.047). There was no significant difference according to pulmonary function test values between 8th week and last trimester (p>0.05), there was a statistical difference between two periods only in terms of FEV1% (p=0.047). No significant difference was found between the mean birth weight of babies of 13 pregnant women with poor sleep quality and mean birth weight of babies of 18 pregnant women with good sleep quality (p=0.565).
Conclusion: As a result, in our study, nearly half of the pregnant women had impaired sleep quality in the last trimester according to the Pittsburg Sleep Quality Index, but birth weight was not affected in pregnant women with poor sleep quality. Sleep quality, the presence of OSAS in pregnancy and its relationship with pregnancy and postpartum complications are not clear, OSAS pregnancy studies should be performed especially involving complicated pregnancies.
Keywords
References
- 1. Facco FL, Parker CB, Reddy UM, Silver RM, Koch MA, Louis JM et al. Association Between Sleep-Disordered Breathing and Hypertensive Disorders of Pregnancy and Gestational Diabetes Mellitus. Obstet Gynecol 2017;129(1):31-41. doi: 10.1097/AOG.0000000000001805.
- 2. Dominguez JE, Krystal AD, Habib AS. Obstructive Sleep Apnea in Pregnant Women: A Review of Pregnancy Outcomes and an Approach to Management. Anesth Analg 2018;127(5):1167-77. doi: 10.1213/ANE.0000000000003335.
- 3. Louis J, Auckley D, Miladinovic B, Shepherd A, Mencin P, Kumar D et al. Perinatal outcomes associated with obstructive sleep apnea in obese pregnant women. Obstet Gynecol 2012;120(5):1085-92. doi: 10.1097/AOG.0b013e31826eb9d8.
- 4. Ursavaş A, Karadağ M. Sleep breathing disorders in pregnancy. Tuberk Toraks 2009;57(2):237-43.
- 5. Kır Şahin F, Köken G, Coşar E, Saylan F, Fidan F, Yılmazer M et al. Gebelikte uyku apne sendromu ve eşlik eden hastalıklar. Turk J Obstet Gynecol 2008;5(1):22- 7.
- 6. Miskovic A, Simpson M, Dominguez JE, Bullough AS. Recognising obstructive sleep apnoea in pregnancy - a survey of UK obstetric anaesthetists. Anaesthesia 2017;72(12):1564. doi: 10.1111/anae.14151.
- 7. Türk Toraks Derneği Obstrüktif Uyku Apne Sendromu Tanı ve Tedavi Uzlaşı Raporu. Ed: Kılınç O, Bayram H. Turk Thorac J 2012; 13 Suppl.1:30-2.
- 8. Izci B, Ardic S, Firat H, Sahin A, Altinors M, Karacan I. Reliability and validity studies of the Turkish version of the Epworth Sleepiness Scale. Sleep Breath 2008;12(2):161-8.
- 9. Abrishami A, Khajehdehi A, Chung F. A systematic review of screening questionnaires for obstructive sleep apnea. Can J Anaesth 2010;57:423-38.
- 10. MacLean AW, Fekken GC, Saskin P, Knowles JB. Psychometric evaluation of the Stanford Sleepiness Scale. J Sleep Res 1992;1:35-9.
- 11. Abrishami A, Khajehdehi A, Chung F. A systematic review of screening questionnaires for obstructive sleep apnea. Can J Anaesth 2010;57:423-38.
- 12. Hutchison BL, Stone PR, McCowan LM, Stewart AW, Thompson JM, Mitchell EA. BMC Pregnancy Childbirth 2012;10(12):144. doi: 10.1186/1471-2393-12-144.
- 13. Ursavas A, Karadag M, Nalci N, Ercan I, Gozu RO. Self-reported snoring, maternal obesity and neck circumference as risk factors for pregnancy-induced hypertension and preeclampsia. Respiration 2008;76(1):33-9.
- 14. Kabil Kucur S, Kucur C, Seven A, Yüksel B, Gözükara İ, Polat M et al. Gebelikte Uyku Apne Sıklığının Değerlendirilmesi. The Journal of Gynocology-Obstetrics and Neonatalogy 2015;12(5):179-82.
- 15. Başoğlu ÖK, Yürekli BS, Taşkıranlar P, Tunçel Ş, Yılmaz C. Ege Obez Hasta Okulu anket çalışması: obezite ile obstrüktif uyku apne sendromu semptomları ve gündüz uykululuk ilişkisi. Ege Journal of Medicine 2011;50(2):111-7.
- 16. Mindell JA, Cook RA, Nikolovski J. Sleep patterns and sleep disturbances across pregnancy. Sleep Med 2015;16(4):483-8. doi: 10.1016/j.sleep.2014.12.006.
- 17. Louis JM, Koch MA, Reddy UM, Silver RM, Parker CB, Facco FL et al. Predictors of sleep-disordered breathing in pregnancy. Am J Obstet Gynecol. 2018;218(5):521.
- 18. Pien GW, Pack AI, Jackson N, Maislin G, Macones GA, Schwab RJ. Risk factors for sleep-disordered breathing in pregnancy. Thorax 2014;69(4):371-7. doi: 10.1136/thoraxjnl-2012-202718.
- 19. Louis JM, Mogos MF, Salemi JL, Redline S, Salihu HM. Obstructive sleep apnea and severe maternal-infant morbidity/mortality in the United States, 1998-2009. Sleep 2014;37(5):843-9. doi: 10.5665/sleep.3644.
- 20. Tantrakul V, Sirijanchune P, Panburana P, Pengjam J, Suwansathit W, Boonsarngsul V et al. Screening of obstructive sleep apnea during pregnancy: differences in predictive values of questionnaires across trimesters. J Clin Sleep Med 2015;11(2):157-63. doi: 10.5664/jcsm.4464.
- 21. Celik F, Kose M. Gebelikte uyku kalitesinin trimester ile ilişkisi. Kocatepe Tıp Derg 2017;18(3):85-88.
- 22. Şahin Köybaşı E, Yeşiltepe Oskay Ü. Gebelik sürecinin uyku kalitesine etkisi. Gülhane Tıp Derg 2017;59:1-5.
- 23. Kahyaoglu Sut H, Asci O, Topac N. Sleep quality and health-related quality of life in pregnancy. J Perinat Neonat Nurs 2016;30(4):302-9.
- 24. Çoban A, Yanıkkerem UE. Gebelerde uyku kalitesi ve yorgunluk düzeyi. Ege Tıp Dergisi 2010;49(2):87-94.
- 25. Sharma SK, Nehra A, Sinha S, Soneja M, Sunesh K, Sreenivas V et al. Sleep disorders in pregnancy and their association with pregnancy outcomes: a prospective observational study. Sleep Breath 2016;20(1):87-93. doi: 10.1007/s11325-015-1188-9.
- 26. Grindheim G, Toska K, Estensen ME, Rosseland LA. Changes in pulmonary function during pregnancy: a longitudinal cohort study. BJOG. 2012;119(1):94-101. doi: 10.1111/j.1471-0528.2011.03158.x.
Details
| Primary Language | English |
|---|---|
| Subjects | Obstetrics and Gynaecology |
| Journal Section | Research Article |
| Authors | |
| Publication Date | September 30, 2022 |
| Submission Date | December 6, 2021 |
| Acceptance Date | August 11, 2022 |
| Published in Issue | Year 2022 Volume: 19 Issue: 3 |
