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Central Retinal Vein Occlusion Following Intravenous Immunoglobulin Treatment in a Patient with Pemphigus Vulgaris

Yıl 2017, Cilt: 70 Sayı: 1, 53 - 56, 21.04.2017

Aysun Şanal Doğan

https://doi.org/10.1501/Tipfak_0000000963

Öz

A 68-year-old male has been treated with prednisolone and intravenous immunoglobulin (IVIG) therapies with the diagnosis of pemphigus vulgaris. When he applied to receive the fifth session of IVIG therapy, he complained about visual loss. On the ophthalmologic examination, left central retinal vein occlusion (CRVO) was determined. There was no other detected underlying cause for CRVO and it was thought that central retinal vein thrombosis might be due to IVIG therapy.

IVIG treatment is generally accepted reliable for pemphigus vulgaris. However, it can rarely cause serious side effects like thrombosis. In literature, there are a few cases of central retinal vein occlusion due to IVIG therapy and none of these have dermatological disease as their etiology. 


Anahtar Kelimeler

Central Retinal Vein Occlusion Intraven ous Immunoglobulin

Kaynakça

  • 1. Schiavo AL, Puca RV, Ruocco V, Ruocco E: Adjuvant drugs in autoimmune bullous diseases, efficacy versus safety: Facts and controversies. Clinics in Dermatology. 2010; 28:337-343.
  • 2. Oh KT, Boldt HC, Danis RP: Iatrogenic central retinal vein occlusion and hyperviscosity associated with high-dose intravenous immunoglobulin administration. Am J Ophthalmol. 1997 ;124:416-418.
  • 3. Harkness KA, Goulding P:Central retinal vein occlusion complicating treatment with intravenous immunoglobulin. Eye(Lond). 2000; 14:662-663.
  • 4. Palacio GL, Gabbai AA, Muccioli C, et al. Images in Medicine. Occlusion of the central vein of the retina after treatment with intravenous human immunoglobulin. Rev Assoc Med Bras. 2004; 50:246.
  • 5. Nawasiwatte BMTP, Somaratne SC, Fernando A, et al. Retinal vein occlusion following intravenous immunoglobulin treatment. Ceylon Medical Journal. 2012; 57:170-171.
  • 6. Gelman R, Dimango EA, Schiff WM: Sequential bilateral central retinal vein occlusions in a cystic fibrosis patient with hyperhomocysteinemia and hypergammaglobulinemia. Retin Cases Brief Rep. 2013; 7:362-367.
  • 7. Lee KY, Lee HS, Hong JH, et all.Highdose intravenous immunoglobulin downregulates the activated levels of inflammatory indices except erythrocyte sedimentation rate in acute stage of Kawasaki Disease. J Trop Pediatr. 2005; 51:98-101.
  • 8. Schussler O, Lantoine F, Devynck MA, et all. Human immunoglobulins inhibit thrombin-induced Ca movements and nitric oxide production in endothelial cells. J Biol Chem. 1996; 271:26473-26476.
  • 9. Bagdasarian A, Tonetta S, Harel W, et all. IVIG adverse reactions: potential role of cytokines and vasoactive substances. Vox Sang. 1998; 74: 74-82.
Toplam 9 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Konular Sağlık Kurumları Yönetimi
Bölüm Makaleler
Yazarlar

Aysun Şanal Doğan

Yayımlanma Tarihi 21 Nisan 2017
Yayımlandığı Sayı Yıl 2017 Cilt: 70 Sayı: 1

Kaynak Göster

APA Şanal Doğan, A. (2017). Central Retinal Vein Occlusion Following Intravenous Immunoglobulin Treatment in a Patient with Pemphigus Vulgaris. Ankara Üniversitesi Tıp Fakültesi Mecmuası, 70(1), 53-56. https://doi.org/10.1501/Tipfak_0000000963
AMA Şanal Doğan A. Central Retinal Vein Occlusion Following Intravenous Immunoglobulin Treatment in a Patient with Pemphigus Vulgaris. Ankara Üniversitesi Tıp Fakültesi Mecmuası. Nisan 2017;70(1):53-56. doi:10.1501/Tipfak_0000000963
Chicago Şanal Doğan, Aysun. “Central Retinal Vein Occlusion Following Intravenous Immunoglobulin Treatment in a Patient With Pemphigus Vulgaris”. Ankara Üniversitesi Tıp Fakültesi Mecmuası 70, sy. 1 (Nisan 2017): 53-56. https://doi.org/10.1501/Tipfak_0000000963.
EndNote Şanal Doğan A (01 Nisan 2017) Central Retinal Vein Occlusion Following Intravenous Immunoglobulin Treatment in a Patient with Pemphigus Vulgaris. Ankara Üniversitesi Tıp Fakültesi Mecmuası 70 1 53–56.
IEEE A. Şanal Doğan, “Central Retinal Vein Occlusion Following Intravenous Immunoglobulin Treatment in a Patient with Pemphigus Vulgaris”, Ankara Üniversitesi Tıp Fakültesi Mecmuası, c. 70, sy. 1, ss. 53–56, 2017, doi: 10.1501/Tipfak_0000000963.
ISNAD Şanal Doğan, Aysun. “Central Retinal Vein Occlusion Following Intravenous Immunoglobulin Treatment in a Patient With Pemphigus Vulgaris”. Ankara Üniversitesi Tıp Fakültesi Mecmuası 70/1 (Nisan 2017), 53-56. https://doi.org/10.1501/Tipfak_0000000963.
JAMA Şanal Doğan A. Central Retinal Vein Occlusion Following Intravenous Immunoglobulin Treatment in a Patient with Pemphigus Vulgaris. Ankara Üniversitesi Tıp Fakültesi Mecmuası. 2017;70:53–56.
MLA Şanal Doğan, Aysun. “Central Retinal Vein Occlusion Following Intravenous Immunoglobulin Treatment in a Patient With Pemphigus Vulgaris”. Ankara Üniversitesi Tıp Fakültesi Mecmuası, c. 70, sy. 1, 2017, ss. 53-56, doi:10.1501/Tipfak_0000000963.
Vancouver Şanal Doğan A. Central Retinal Vein Occlusion Following Intravenous Immunoglobulin Treatment in a Patient with Pemphigus Vulgaris. Ankara Üniversitesi Tıp Fakültesi Mecmuası. 2017;70(1):53-6.