Endometrium Kanserinde Myometrial İnvazyon Derinliğinin Magnetik Rezonans Görüntüleme ile Değerlendirilmesi
Öz
Amaç: Endometrium kanseri (EK)
tanısı almış hastalarda, ameliyat öncesi myometrial invazyon (Mİ)’nun saptanmasında
magnetik rezonans görüntülemenin ( MRG) değerinin araştırılması amaçlandı.
Yöntem: Endometrium kanseri tanısı
alan hastalardan ameliyat öncesi MR görüntüleme yapılanlar çalışmaya dahil
edildi. Hastaların görüntüleme bilgileri, operasyon bilgileri, patoloji
sonuçları dosyalarından alınarak kaydedildi. MRG raporlarında myometrial
invazyon durumları ile ameliyat sonrası patolojik incelemede tespit edilen
myometrial invazyon durumları karşılaştırılarak MRG’nin endometrium kanserinde
myometrial invazyon varlığını tahmin etmedeki rolü değerlendirildi.
Bulgular:
Ameliyat öncesi MR ile görüntüleme yapılan 302 hasta çalışmaya dahil edildi.
Hastaların yaşları 29 -90 arasında olup, ortalama 59.5+-10.7 bulundu. Bu
hastalar endometrial biyopsi yapılarak endometrium kanseri tanısı almıştı. MR
yöntemi ile endometrium kanseri tanılı hastada myometrial invazyon tespitinde
duyarlılık (%78.43), özgüllük (%93.23), doğruluk (%81.12) olarak tespit edildi.
Sonuç: EK’inde Mİ varlığını
değerlendirmede, ameliyat öncesi MR görüntülemenin önemli bir yöntem olduğu
izlendi.
Anahtar Kelimeler
Magnetik rezonans görüntüleme endometrium kanseri miyometrial invazyon.
Kaynakça
- 1. Cetinkaya K, Atalay F, Bacinoglu A. Risk factors of lymph node metastases with endometrial carcinoma Asian Pas J Can Prev, 2014,15:6353- 56.
- 2. Chambers SK, Kapp DS, Peschel RE, et al: Prognostic factors and sites of failure in FIGO stage I, grade III endometrial carcinoma. Gynecol Oncol 1987; 27: 180.
- 3. Sironi S, Taccagni G, Garancini P, et al. Myometrial invasion by endometrial carcinoma: assesment with MRI. AJR 1992; 158: 565– 569.
- 4. Morrow CP, Bundy BN, Kumar RJ. Relationship between surgical-pathological risk factors and outcome in clinical stages 1 and 2 carcinoma of the endometrium A Gynecol Oncol Group Study. Gynecol Oncol 1991; 40: 55.
- 5. Reagan JW, Fu YS. Pathology of endometrial carcinoma. In Coppleson M. (ed): Gynecol Oncol. Churchill Livingstone, Edinburg 1981.
- 6. R.C. Boronow, C.P. Morrow, W.T. Creasman, P.J. Disaia, S.G. Silverberg,A.Miller, A.Blessing, Surgical Staging in Endometrial Cancer: ClinicalPathologic Finding of a Prospective Study, Obstet & Gynecol, 1984;63:825-832.
- 7. Sironi S., Taccagni G., Garancini P., et al:Myometrial invasion by endometrial carcinoma :Assessment by MR imaging.AJR 1992;158:565-569.
- 8. Yamashita Y.,Harada M.,Sawada T.,Takahashi M.,Miyazaki K.,Okamura H:Normal uterus and FİGO Stage I endometrial carcinoma:Dynamic gadolinume enhanced MRI.Radiology 1993;186:495-501.
- 9. Hricak H., Stern J.L., Fisher M.R., Shapeero L.G., Winkler M.L., Lacey C.G. Endometrial carcinoma staging by MR imaging. Radiology 1987; 162:297-305.
- 10. Lien H.H., Blomlie V., Trope C., Kaern J., Abeler V.M. Cancer of the endometrium: value of MR imaging in determining depth of invasion into the myometrium. AJR Am J Roentgenol 1991; 157:1221-1223.
- 11. Chung H.H., Kang S.B., Cho J.Y., et al. Accuracy of MR imaging for the prediction of myometrial invasion of endometrial carcinoma. Gynecol Oncol 2007; 104:654-659.
- 12. Zamani F., Goodarzi S., Hallaji F., et al. Diagnostic Value of Pelvic MRI for Assessment of the Depth of Myometrial Invasion and Cervical Involvement in Endometrial Cancer: Comparison of New Versus Old FIGO Staging. Iran J Radiol 2012; 9:202-208.
- 13. Cabrita S., Rodrigues H., Abreu R., et al. Magnetic resonance imaging in the preoperative staging of endometrial carcinoma. Eur J Gynea Oncol 2007:135-137.
- 14. Vasconcelos C., Félix A., Cunha T.M. Preoperative assessment of deep myometrial and cervical invasion in endometrial carcinoma: Comparison of magnetic resonance imaging and histopathologic evaluation. Journal of Obstetrics & Gynaecology 2007; 27:65-70
Öz
Aim: The aim of this study is to investigate the value of
magnetic resonans imaging (MRI) for detecting preoperative myometrial invasion
(Ml) in endometrial (EC) cancer patients.
Material
and Methods:
Among EC patients with preoperative MRI were included in this study. The data
of patients were recorded from their files. MRI reports and MI status in final
pathological examination after surgery were compared. The predicting value of
MRI for MI presence was evaluated.
Results:
Totally, 302 patients who
were obtained preoperative MRI enrolled into the study. The age of the patients
were between 29-90, mean 59.5±10,7. The EC was diagnosed by endometial biopsy.
The sensitivity, specifity and diagnostic accuracy of MRI assessment of MI were
78.43%, 93.23% and 81.12%, respectively.
Conclusion:
The assessment of the MI
presence in EC patients by preoperative MRI is a valuable method.
Anahtar Kelimeler
Magnetic resonance imaging endometrial cancer myometrial invasion
Kaynakça
- 1. Cetinkaya K, Atalay F, Bacinoglu A. Risk factors of lymph node metastases with endometrial carcinoma Asian Pas J Can Prev, 2014,15:6353- 56.
- 2. Chambers SK, Kapp DS, Peschel RE, et al: Prognostic factors and sites of failure in FIGO stage I, grade III endometrial carcinoma. Gynecol Oncol 1987; 27: 180.
- 3. Sironi S, Taccagni G, Garancini P, et al. Myometrial invasion by endometrial carcinoma: assesment with MRI. AJR 1992; 158: 565– 569.
- 4. Morrow CP, Bundy BN, Kumar RJ. Relationship between surgical-pathological risk factors and outcome in clinical stages 1 and 2 carcinoma of the endometrium A Gynecol Oncol Group Study. Gynecol Oncol 1991; 40: 55.
- 5. Reagan JW, Fu YS. Pathology of endometrial carcinoma. In Coppleson M. (ed): Gynecol Oncol. Churchill Livingstone, Edinburg 1981.
- 6. R.C. Boronow, C.P. Morrow, W.T. Creasman, P.J. Disaia, S.G. Silverberg,A.Miller, A.Blessing, Surgical Staging in Endometrial Cancer: ClinicalPathologic Finding of a Prospective Study, Obstet & Gynecol, 1984;63:825-832.
- 7. Sironi S., Taccagni G., Garancini P., et al:Myometrial invasion by endometrial carcinoma :Assessment by MR imaging.AJR 1992;158:565-569.
- 8. Yamashita Y.,Harada M.,Sawada T.,Takahashi M.,Miyazaki K.,Okamura H:Normal uterus and FİGO Stage I endometrial carcinoma:Dynamic gadolinume enhanced MRI.Radiology 1993;186:495-501.
- 9. Hricak H., Stern J.L., Fisher M.R., Shapeero L.G., Winkler M.L., Lacey C.G. Endometrial carcinoma staging by MR imaging. Radiology 1987; 162:297-305.
- 10. Lien H.H., Blomlie V., Trope C., Kaern J., Abeler V.M. Cancer of the endometrium: value of MR imaging in determining depth of invasion into the myometrium. AJR Am J Roentgenol 1991; 157:1221-1223.
- 11. Chung H.H., Kang S.B., Cho J.Y., et al. Accuracy of MR imaging for the prediction of myometrial invasion of endometrial carcinoma. Gynecol Oncol 2007; 104:654-659.
- 12. Zamani F., Goodarzi S., Hallaji F., et al. Diagnostic Value of Pelvic MRI for Assessment of the Depth of Myometrial Invasion and Cervical Involvement in Endometrial Cancer: Comparison of New Versus Old FIGO Staging. Iran J Radiol 2012; 9:202-208.
- 13. Cabrita S., Rodrigues H., Abreu R., et al. Magnetic resonance imaging in the preoperative staging of endometrial carcinoma. Eur J Gynea Oncol 2007:135-137.
- 14. Vasconcelos C., Félix A., Cunha T.M. Preoperative assessment of deep myometrial and cervical invasion in endometrial carcinoma: Comparison of magnetic resonance imaging and histopathologic evaluation. Journal of Obstetrics & Gynaecology 2007; 27:65-70
Ayrıntılar
| Birincil Dil | Türkçe |
|---|---|
| Konular | Klinik Tıp Bilimleri |
| Bölüm | Araştırma Makalesi |
| Yazarlar | |
| Yayımlanma Tarihi | 29 Ağustos 2019 |
| Kabul Tarihi | 6 Ağustos 2019 |
| Yayımlandığı Sayı | Yıl 2019 Cilt: 3 Sayı: 2 |
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