Öz
üzerindeki etkilerini incelemektedir.
The microbiota is the collective community of microorganisms that live on or within an organism, its environment and its habitats. These microorganisms include bacteria, archaea, fungi, viruses and other microscopic organisms. Microbiota generally refers to organisms that exist in natural systems and have a mutualistic relationship with the host organism. In particular, the intestinal microbiota exists as a large bacterial colony in the intestines and helps digestive processes. It may also play an important role in regulating the immune system. A better understanding of the gut microbiota may help discover potential new approaches to the treatment and prevention of various diseases and health conditions. For this reason, research and discoveries related to microbiota are an important focus of interest in the scientific world and the medical field. This article; examines the effects of intestinal microbiota on the cardiovascular, endocrine and nervous systems.
Anahtar Kelimeler
Intestinal microbiota cardiovascular system endocrine system neurological system
Proje Numarası
Dönem 2 öğrencileri ile Deleme makale raporu hazırlama
Kaynakça
- Boulangé CL, Neves AL, Chilloux J, Nicholson JK, Dumas ME. Impact of the gut microbiota on inflammation, obesity, and metabolic disease. Genome Med. 2016;8(1):42.
- Fabozzi G, Rebuzzini P, Cimadomo D, et al. Endocrine- disrupting chemicals, gut microbiota, and human (In) fertility-It is time to consider the triad. Cells. 2022;11(21):3335.
- Palmnäs-Bédard MSA, Costabile G, Vetrani C, et al. The human gut microbiota and glucose metabolism: A scoping review of key bacteria and the potential role of SCFAs. Am J Clin Nutr. 2022;116(4):862-874.
- Kant R, Chandra L, Verma V, et al. Gut microbiota interactions with anti-diabetic medications and pathogenesis of type 2 diabetes mellitus. World J Methodol. 2022;12(4):246-257.
- Liu Q, Sun W, Zhang H. Interaction of gut microbiota with endocrine homeostasis and thyroid cancer. Cancers. 2022;14(11):2656.
- Knezevic J, Starchl C, Tmava Berisha A, Amrein K. Thyroid-gut-axis: How does the microbiota influence thyroid function? Nutrients. 2020;12(6):1769.
- Zheng D, Liwinski T, Elinav E. Interaction between microbiota and immunity in health and disease. Cell Res. 2020;30:492-506.
- Hassan D, Zahra T, Kanaan G, Khan MU, Mushtaq K, Nashwan AJ, Hamid PF. The impact of gut microbiome constitution to reduce cardiovascular disease risk: A systematic review and meta-analysis. Curr Probl Cardiol. 2023;48(2):101459.
- Liu Y, Zheng G, Jin X, Fan T, Chen Z, Sheng X. Influence of gut microbiota and trimethylamine N-oxide in patients with coronary heart disease. Int Heart J. 2022;63(4):683- 691.
- Jie Z, Xia H, Zhong SL, et al. The gut microbiome in atherosclerotic cardiovascular disease. Nat Commun. 2017;8(1):845.
- Hodzic A, Oudah M. Microbiome classification for heart disease detection," 2022 IEEE 22nd International Conference on Bioinformatics and Bioengineering (BIBE), Taichung, Taiwan, 2022;237-242.
- Cao H, Zhu Y, Hu G, Zhang Q, Zheng L. Gut microbiome and metabolites, the future direction of diagnosis and treatment of atherosclerosis? Pharmacol Res. 2023;187:106586.
- Ufnal M, Zadlo A, Ostaszewski R. TMAO: A small molecule of great expectations. Nutrition. 2015;31(11- 12):1317-1323.
- Chen Y, Xu J, Chen Y. Regulation of neurotransmitters by the gut microbiota and effects on cognition in neurological disorders. Nutrients. 2021;13(6):2099.
- Castillo-Álvarez F, Marzo-Sola ME. Role of the gut microbiota in the development of various neurological diseases. Neurologia (Engl Ed). 2022;37(6):492-498.
- Generoso JS, Giridharan VV, Lee J, Macedo D, Barichello T. The role of the microbiota-gut-brain axis in neuropsychiatric disorders. Braz J Psychiatry. 2021;43(3):293-305.
- Westfall S, Lomis N, Kahouli I, Dia SY, Singh SP, Prakash S. Microbiome, probiotics and neurodegenerative diseases: Deciphering the gut brain axis. Cell Mol Life Sci. 2017;74(20):3769-3787.
- Santos-Lozano A, Pareja-Galeano H, Sanchis-Gomar F, et al. Physical activity and Alzheimer disease: A protective association. Mayo Clin Proc. 2016;91(8):999-1020.
- Du Z, Li Y, Li J, Zhou C, Li F, Yang X. Physical activity can improve cognition in patients with Alzheimer's disease: A systematic review and meta-analysis of randomized controlled trials. Clin Interv Aging. 2018;13:1593-1603.
- Dalton A, Mermier C, Zuhl M. Exercise influence on the microbiome gut brain axis. Gut Microbes. 2019;10(5):555-558.
- Mitchell CM, Davy BM, Hulver MW, Neilson AP, Bennett BJ, Davy KP. Does exercise alter gut microbial composition? A systematic review. Med. Sci. Sports Exerc. 2019;51(1):160-167.
- Kang SS, Jeraldo PR, Kurti A, et al. Diet and exercise orthogonally alter the gut microbiome and reveal independent associations with anxiety and cognition. Mol. Neurodegener. 2014;9:36.
- Hou K, Wu ZX, Chen XY, et al. Microbiota in health and diseases. Signal Transduct Target Ther. 2022;7(1):135.
- Gubert C, Kong G, Renoir T, Hannan AJ. Exercise, diet and stress as modulators of gut microbiota: Implications for neurodegenerative diseases. Neurobiol Dis. 2020;134:10462.
Öz
Mikrobiyota, bir organizmanın, onun çevresinin ve habitatlarının üzerinde veya içinde yaşayan mikroorganizmaların kolektif topluluğudur. Bu mikroorganizmalar bakterileri, arkeaları, mantarları, virüsleri ve diğer mikroskobik organizmaları içerir. Mikrobiyota genellikle doğal sistemlerde var olan ve konakçı organizma ile karşılıklı bir ilişkiye sahip olan organizmaları ifade eder. Özellikle bağırsak mikrobiyotası bağırsaklarda geniş bir bakteri kolonisi olarak bulunur ve sindirim süreçlerine yardımcı olur. Ayrıca bağışıklık sisteminin düzenlenmesinde de önemli bir rol oynayabilir. Bağırsak mikrobiyotasının daha iyi anlaşılması, çeşitli hastalıkların ve sağlık durumlarının tedavisi ve önlenmesine yönelik potansiyel yeni yaklaşımların keşfedilmesine yardımcı olabilir. Bu nedenle mikrobiyota ile ilgili araştırma ve keşifler bilim dünyasının ve tıp alanının önemli bir ilgi odağıdır. Bu makalede; bağırsak mikrobiyotasının kardiyovasküler, endokrin ve sinir sistemi üzerindeki etkilerini incelemektedir.
Anahtar Kelimeler
Bağırsak mikrobiyotası kardiyovasküler sistem endokrin sistem nörolojik sistem
Etik Beyan
Bu derleme için etik onay alınmamıştır. Derlemede kullanılan tüm kaynaklar makale içinde belirtilmiştir. Kaynak kısmında da yazılmışlardır
Destekleyen Kurum
-
Proje Numarası
Dönem 2 öğrencileri ile Deleme makale raporu hazırlama
Teşekkür
-
Kaynakça
- Boulangé CL, Neves AL, Chilloux J, Nicholson JK, Dumas ME. Impact of the gut microbiota on inflammation, obesity, and metabolic disease. Genome Med. 2016;8(1):42.
- Fabozzi G, Rebuzzini P, Cimadomo D, et al. Endocrine- disrupting chemicals, gut microbiota, and human (In) fertility-It is time to consider the triad. Cells. 2022;11(21):3335.
- Palmnäs-Bédard MSA, Costabile G, Vetrani C, et al. The human gut microbiota and glucose metabolism: A scoping review of key bacteria and the potential role of SCFAs. Am J Clin Nutr. 2022;116(4):862-874.
- Kant R, Chandra L, Verma V, et al. Gut microbiota interactions with anti-diabetic medications and pathogenesis of type 2 diabetes mellitus. World J Methodol. 2022;12(4):246-257.
- Liu Q, Sun W, Zhang H. Interaction of gut microbiota with endocrine homeostasis and thyroid cancer. Cancers. 2022;14(11):2656.
- Knezevic J, Starchl C, Tmava Berisha A, Amrein K. Thyroid-gut-axis: How does the microbiota influence thyroid function? Nutrients. 2020;12(6):1769.
- Zheng D, Liwinski T, Elinav E. Interaction between microbiota and immunity in health and disease. Cell Res. 2020;30:492-506.
- Hassan D, Zahra T, Kanaan G, Khan MU, Mushtaq K, Nashwan AJ, Hamid PF. The impact of gut microbiome constitution to reduce cardiovascular disease risk: A systematic review and meta-analysis. Curr Probl Cardiol. 2023;48(2):101459.
- Liu Y, Zheng G, Jin X, Fan T, Chen Z, Sheng X. Influence of gut microbiota and trimethylamine N-oxide in patients with coronary heart disease. Int Heart J. 2022;63(4):683- 691.
- Jie Z, Xia H, Zhong SL, et al. The gut microbiome in atherosclerotic cardiovascular disease. Nat Commun. 2017;8(1):845.
- Hodzic A, Oudah M. Microbiome classification for heart disease detection," 2022 IEEE 22nd International Conference on Bioinformatics and Bioengineering (BIBE), Taichung, Taiwan, 2022;237-242.
- Cao H, Zhu Y, Hu G, Zhang Q, Zheng L. Gut microbiome and metabolites, the future direction of diagnosis and treatment of atherosclerosis? Pharmacol Res. 2023;187:106586.
- Ufnal M, Zadlo A, Ostaszewski R. TMAO: A small molecule of great expectations. Nutrition. 2015;31(11- 12):1317-1323.
- Chen Y, Xu J, Chen Y. Regulation of neurotransmitters by the gut microbiota and effects on cognition in neurological disorders. Nutrients. 2021;13(6):2099.
- Castillo-Álvarez F, Marzo-Sola ME. Role of the gut microbiota in the development of various neurological diseases. Neurologia (Engl Ed). 2022;37(6):492-498.
- Generoso JS, Giridharan VV, Lee J, Macedo D, Barichello T. The role of the microbiota-gut-brain axis in neuropsychiatric disorders. Braz J Psychiatry. 2021;43(3):293-305.
- Westfall S, Lomis N, Kahouli I, Dia SY, Singh SP, Prakash S. Microbiome, probiotics and neurodegenerative diseases: Deciphering the gut brain axis. Cell Mol Life Sci. 2017;74(20):3769-3787.
- Santos-Lozano A, Pareja-Galeano H, Sanchis-Gomar F, et al. Physical activity and Alzheimer disease: A protective association. Mayo Clin Proc. 2016;91(8):999-1020.
- Du Z, Li Y, Li J, Zhou C, Li F, Yang X. Physical activity can improve cognition in patients with Alzheimer's disease: A systematic review and meta-analysis of randomized controlled trials. Clin Interv Aging. 2018;13:1593-1603.
- Dalton A, Mermier C, Zuhl M. Exercise influence on the microbiome gut brain axis. Gut Microbes. 2019;10(5):555-558.
- Mitchell CM, Davy BM, Hulver MW, Neilson AP, Bennett BJ, Davy KP. Does exercise alter gut microbial composition? A systematic review. Med. Sci. Sports Exerc. 2019;51(1):160-167.
- Kang SS, Jeraldo PR, Kurti A, et al. Diet and exercise orthogonally alter the gut microbiome and reveal independent associations with anxiety and cognition. Mol. Neurodegener. 2014;9:36.
- Hou K, Wu ZX, Chen XY, et al. Microbiota in health and diseases. Signal Transduct Target Ther. 2022;7(1):135.
- Gubert C, Kong G, Renoir T, Hannan AJ. Exercise, diet and stress as modulators of gut microbiota: Implications for neurodegenerative diseases. Neurobiol Dis. 2020;134:10462.
Ayrıntılar
| Birincil Dil | Türkçe |
|---|---|
| Konular | Sağlık Hizmetleri ve Sistemleri (Diğer) |
| Bölüm | Derleme |
| Yazarlar | |
| Proje Numarası | Dönem 2 öğrencileri ile Deleme makale raporu hazırlama |
| Yayımlanma Tarihi | 24 Nisan 2024 |
| Gönderilme Tarihi | 6 Aralık 2023 |
| Kabul Tarihi | 27 Şubat 2024 |
| Yayımlandığı Sayı | Yıl 2024 Cilt: 26 Sayı: 1 |
Kaynak Göster
Bu Dergi, Kırıkkale Üniversitesi Tıp Fakültesi Yayınıdır.