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The association between medication adherence and quality of life in patients with diabetes receiving primary healthcare centers: A cross-sectional study

Yıl 2023, Cilt: 17 Sayı: 3 - Turkish Journal of Family Medicine and Primary Care, 360 - 369, 20.09.2023
https://doi.org/10.21763/tjfmpc.1312415

Öz

Aim: This study aimed to evaluate the association between medication adherence and quality of life in patients with diabetes receiving primary healthcare centers.
Method: Patients with type 2 diabetes, aged 18-65 between July and October 2022, were included in this cross-sectional study. A questionnaire including sociodemographic characteristics, the Diabetes Quality of Life (DQOL) scale, and the Modified Morisky Scale (MMS) were used.
Results: Two hundred nine patients with type 2 diabetes participated in this study. The mean age of the participants was 53.5±9.2 years, and 51.7% were women. The mean DQOL score of the participants was 3.8±0.7. Quality of life was higher among married participants and those with medium-high income, diagnosed with diabetes <5 years previously, without diabetes complications, using only oral antidiabetic drugs for the treatment of diabetes, who regularly used diabetes medications, who dieted and exercised for diabetes, and who regularly attended diabetes follow-up (p<0.05). Quality of life was also higher in those with better MMS showing a better medication adherence motivation and knowledge levels (p<0.01).
Conclusions: Participants' medication adherence motivation and knowledge levels were associated with an increased quality of life. Admission to primary healthcare centers for diabetes follow-up was also associated with a higher quality of life.

Destekleyen Kurum

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Kaynakça

  • 1. International Diabetes Federation. IDF Diabetes Atlas, 10th edn. Brussels, Belgium: (2021) (15.10.2022) https://www.diabetesatlas.org. Accessed.
  • 2. Yılmaz MB, Kılıçkap M, Abacı A, et al. Türkiye’de diabetes mellitus epidemiyolojisinin zamana bağlı değişimi: Bir sistematik derleme ve meta-analiz. Turk Kardiyol Dern Ars. 2018;46(7):546-555.
  • 3. Cramer JA. A systematic review of adherence with medications for diabetes. Diabetes Care. 2004;27(5):1218-1224.
  • 4. da Mata AR, Alvares J, Diniz LM, et al. Quality of life of patients with Diabetes Mellitus Types 1 and 2 from a referal health centre in Minas Gerais, Brazil. Expert Rev Clin Pharmacol. 2016;9(5):739-746.
  • 5. Khayyat SM, Mohamed MMA, Khayyat SMS, et al. Association between medication adherence and quality of life of patients with diabetes and hypertension attending primary care clinics: a cross-sectional survey. Qual Life Res. 2019;28(4):1053-1061.
  • 6. Ho PM, Rumsfeld JS, Masoudi FA, et al. Effect of medication nonadherence on hospitalization and mortality among patients with diabetes mellitus. Arch Intern Med. 2006;166(17):1836-1841.
  • 7. Williams JL, Walker RJ, Smalls BL, Campbell JA, Egede LE. Effective interventions to improve medication adherence in Type 2 diabetes: a systematic review. Diabetes Manag (Lond). 2014;4(1):29-48.
  • 8. Adriaanse MC, Drewes HW, van der Heide I, Struijs JN, Baan CA. The impact of comorbid chronic conditions on quality of life in type 2 diabetes patients. Qual Life Res. 2016;25(1):175-182.
  • 9. Jannoo Z, Wah YB, Lazim AM, Hassali MA. Examining diabetes distress, medication adherence, diabetes self-care activities, diabetes-specific quality of life and health-related quality of life among type 2 diabetes mellitus patients. J Clin Transl Endocrinol. 2017;9:48-54.
  • 10. Akinci F, Yildirim A, Gozu H, Sargin H, Orbay E, Sargin M. Assessment of health-related quality of life (HRQoL) of patients with type 2 diabetes in Turkey. Diabetes Res Clin Pract. 2008;79(1):117-123.
  • 11. Yildirim A, Akinci F, Gozu H, Sargin H, Orbay E, Sargin M. Translation, cultural adaptation, cross-validation of the Turkish diabetes quality-of-life (DQOL) measure. Qual Life Res. 2007;16(5):873-879.
  • 12. Jaam M, Mohamed Ibrahim MI, Kheir N, Hadi MA, Diab MI, Awaisu A. Assessing prevalence of and barriers to medication adherence in patients with uncontrolled diabetes attending primary healthcare clinics in Qatar. Prim Care Diabetes. 2018;12(2):116-125.
  • 13. Vural B, Acar ÖT, Topsever P, Filiz TM. [Reliability And Validity Of Turkish Version Of Modified Morisky Scale]. The Journal of Turkish Family Physician. 2012;3(4):17-20.
  • 14. DCCT Research Group. Reliability and validity of a diabetes quality-of-life measure for the diabetes control and complications trial (DCCT). The DCCT Research Group. Diabetes Care. 1988;11(9):725-732.
  • 15. Morisky DE, Green LW, Levine DM. Concurrent and predictive validity of a self-reported measure of medication adherence. Med Care. 1986;24(1):67-74.
  • 16. Vlasnik JJ, Aliotta SL, DeLor B. Evidence-based assessment and intervention strategies to increase adherence to prescribed medication plans. Case Manager. 2005;16(2):55-59.
  • 17. Gonen S, Gungor K, Cilli AS, et al. Comprehensive Analysis of Health Related Quality of Life in Patients with Diabetes: A Study From Konya Turkey. Turkish Journal of Endocrinology and Metabolism. 2007;11(3):81-88.
  • 18. Fischer MA, Stedman MR, Lii J, et al. Primary medication non-adherence: analysis of 195,930 electronic prescriptions. J Gen Intern Med. 2010;25(4):284-290.
  • 19. Bradley C, Eschwege E, de Pablos-Velasco P, et al. Predictors of Quality of Life and Other Patient-Reported Outcomes in the Panorama Multinational Study of People With Type 2 Diabetes. Diabetes Care. 2018;41(2):267-276.
  • 20. Pinto DM, Santiago LM, Maurício K, Silva IR. Health profile and medication adherence of diabetic patients in the Portuguese population. Prim Care Diabetes. 2019;13(5):446-451.
  • 21. Trief PM, Kalichman SC, Wang D, et al. Medication adherence in young adults with youth-onset type 2 diabetes: iCount, an observational study. Diabetes Res Clin Pract. 2022;184:109216.
  • 22. Diriba DC, Leung DYP, Suen LKP. Cultural Adaptation and Psychometric Properties of the Diabetes Quality of Life Scale in Afaan Oromoo among People Living with Type 2 Diabetes in Ethiopia. International Journal of Environmental Research and Public Health. 2021;18(14):16.
  • 23. Rwegerera GM, Moshomo T, Gaenamong M, et al. Health-related quality of life and associated factors among patients with diabetes mellitus in Botswana. Alexandria Journal of Medicine. 2018;54(2):111-118.
  • 24. Papadopoulos AA, Kontodimopoulos N, Frydas A, Ikonomakis E, Niakas D. Predictors of health-related quality of life in type II diabetic patients in Greece. BMC Public Health. 2007;7(1):186.
  • 25. A S, Koppad R, Sv C, Revathy R. Quality of life of type 2 diabetes patients in a tertiary care hospital in southern part of India, Shimoga, Karnataka: a cross-sectional study. International Journal of Community Medicine and Public Health. 2016;3(7):1723-1728.
  • 26. Timar R, Velea I, Timar B, et al. Factors influencing the quality of life perception in patients with type 2 diabetes mellitus. Patient Prefer Adherence. 2016;10:2471-2477.
  • 27. Akyol Güner T, Günter T. Diyabetli Bireylerde Beslenme Okuryazarlığının Yaşam Kalitesi ve Metabolik Kontrol Üzerine Etkisi. Online Turkish Journal of Health Sciences (OTJHS). 2022;7(1).
  • 28. Thomas Z, Mathew A, Jowil G, et al. Quality of life among those with diabetes mellitus type II attending a secondary outpatient facility in South India. Journal of Family Medicine and Primary Care. 2022;11(11):7204.
  • 29. Yumın ET, Bakar Y, Şimşek TT. Tip 2 Diyabeti Olan Hastalarda Diyabetin Yaşam Kalitesi Üzerine Etkisi. Turkiye Klinikleri Journal of Sports Sciences. 2017;9(2).
  • 30. Majeed A, Rehman M, Hussain I, et al. The Impact of Treatment Adherence on Quality of Life Among Type 2 Diabetes Mellitus Patients - Findings from a Cross-Sectional Study. Patient Prefer Adherence. 2021;15:475-481.
  • 31. Honish A, Westerfield W, Ashby A, Momin S, Phillippi R. Health-related quality of life and treatment compliance with diabetes care. Dis Manag. 2006;9(4):195-200.
  • 32. Perwitasari DA, Urbayatun S. Treatment Adherence and Quality of Life in Diabetes Mellitus Patients in Indonesia. SAGE Open. 2016;6(2):1-7.

Birinci basamakta tip 2 diyabet hastalarının ilaç uyumu ve yaşam kalitesi ilişkisi: Kesitsel bir çalışma

Yıl 2023, Cilt: 17 Sayı: 3 - Turkish Journal of Family Medicine and Primary Care, 360 - 369, 20.09.2023
https://doi.org/10.21763/tjfmpc.1312415

Öz

Amaç: Bu çalışmada, birinci basamakta tip 2 diyabet hastalarının ilaç uyumu ve yaşam kalitesi ilişkisinin değerlendirilmesi amaçlandı. Yöntem: Bu kesitsel tipte çalışmaya Temmuz-Ekim 2022 tarihleri arasında 18-65 yaş arası tip 2 diyabet hastaları dahil edildi. Katılımcılara bir anket uygulandı. Ankette sosyodemografik özellikler, Diyabet Yaşam Kalitesi Ölçeği (DYKÖ) ve Modifiye Morisky Ölçeği (MMÖ) yer aldı.
Bulgular: Çalışmaya toplam 209 tip 2 diyabet hastası katıldı. Katılımcıların yaş ortalaması 53,5±9,2 yıl ve %51,7’si kadındı. Katılımcıların DYKÖ puan ortalaması 3,8±0,7 bulundu. MMÖ ortalama puanı 4,09±2,09 bulundu. Katılımcılardan evli olanların, gelir durumu orta-yüksek olanların, diyabet tanı süresi <5 yıl olanların, diyabet komplikasyonu olmayanların, diyabet tedavisi olarak sadece oral antidiyabetik kullananların, diyabet ilaçlarını düzenli kullananların, diyabete yönelik diyet ve egzersiz yapanların ve diyabet kontrollerine düzenli gidenlerin yaşam kalitesi daha yüksek bulundu (p<0,05). MMÖ ilaç uyumu motivasyon düzeyi ve bilgi düzeyi yüksek olanların yaşam kalitesi daha yüksek bulundu (p<0,01).
Sonuç: Katılımcıların ilaç uyumu motivasyon ve bilgi düzeyleri artan yaşam kalitesi ile ilişkiliydi. Diyabet kontrolleri için birinci basamağa başvuru yüksek yaşam kalitesi ile ilişkiliydi.

Kaynakça

  • 1. International Diabetes Federation. IDF Diabetes Atlas, 10th edn. Brussels, Belgium: (2021) (15.10.2022) https://www.diabetesatlas.org. Accessed.
  • 2. Yılmaz MB, Kılıçkap M, Abacı A, et al. Türkiye’de diabetes mellitus epidemiyolojisinin zamana bağlı değişimi: Bir sistematik derleme ve meta-analiz. Turk Kardiyol Dern Ars. 2018;46(7):546-555.
  • 3. Cramer JA. A systematic review of adherence with medications for diabetes. Diabetes Care. 2004;27(5):1218-1224.
  • 4. da Mata AR, Alvares J, Diniz LM, et al. Quality of life of patients with Diabetes Mellitus Types 1 and 2 from a referal health centre in Minas Gerais, Brazil. Expert Rev Clin Pharmacol. 2016;9(5):739-746.
  • 5. Khayyat SM, Mohamed MMA, Khayyat SMS, et al. Association between medication adherence and quality of life of patients with diabetes and hypertension attending primary care clinics: a cross-sectional survey. Qual Life Res. 2019;28(4):1053-1061.
  • 6. Ho PM, Rumsfeld JS, Masoudi FA, et al. Effect of medication nonadherence on hospitalization and mortality among patients with diabetes mellitus. Arch Intern Med. 2006;166(17):1836-1841.
  • 7. Williams JL, Walker RJ, Smalls BL, Campbell JA, Egede LE. Effective interventions to improve medication adherence in Type 2 diabetes: a systematic review. Diabetes Manag (Lond). 2014;4(1):29-48.
  • 8. Adriaanse MC, Drewes HW, van der Heide I, Struijs JN, Baan CA. The impact of comorbid chronic conditions on quality of life in type 2 diabetes patients. Qual Life Res. 2016;25(1):175-182.
  • 9. Jannoo Z, Wah YB, Lazim AM, Hassali MA. Examining diabetes distress, medication adherence, diabetes self-care activities, diabetes-specific quality of life and health-related quality of life among type 2 diabetes mellitus patients. J Clin Transl Endocrinol. 2017;9:48-54.
  • 10. Akinci F, Yildirim A, Gozu H, Sargin H, Orbay E, Sargin M. Assessment of health-related quality of life (HRQoL) of patients with type 2 diabetes in Turkey. Diabetes Res Clin Pract. 2008;79(1):117-123.
  • 11. Yildirim A, Akinci F, Gozu H, Sargin H, Orbay E, Sargin M. Translation, cultural adaptation, cross-validation of the Turkish diabetes quality-of-life (DQOL) measure. Qual Life Res. 2007;16(5):873-879.
  • 12. Jaam M, Mohamed Ibrahim MI, Kheir N, Hadi MA, Diab MI, Awaisu A. Assessing prevalence of and barriers to medication adherence in patients with uncontrolled diabetes attending primary healthcare clinics in Qatar. Prim Care Diabetes. 2018;12(2):116-125.
  • 13. Vural B, Acar ÖT, Topsever P, Filiz TM. [Reliability And Validity Of Turkish Version Of Modified Morisky Scale]. The Journal of Turkish Family Physician. 2012;3(4):17-20.
  • 14. DCCT Research Group. Reliability and validity of a diabetes quality-of-life measure for the diabetes control and complications trial (DCCT). The DCCT Research Group. Diabetes Care. 1988;11(9):725-732.
  • 15. Morisky DE, Green LW, Levine DM. Concurrent and predictive validity of a self-reported measure of medication adherence. Med Care. 1986;24(1):67-74.
  • 16. Vlasnik JJ, Aliotta SL, DeLor B. Evidence-based assessment and intervention strategies to increase adherence to prescribed medication plans. Case Manager. 2005;16(2):55-59.
  • 17. Gonen S, Gungor K, Cilli AS, et al. Comprehensive Analysis of Health Related Quality of Life in Patients with Diabetes: A Study From Konya Turkey. Turkish Journal of Endocrinology and Metabolism. 2007;11(3):81-88.
  • 18. Fischer MA, Stedman MR, Lii J, et al. Primary medication non-adherence: analysis of 195,930 electronic prescriptions. J Gen Intern Med. 2010;25(4):284-290.
  • 19. Bradley C, Eschwege E, de Pablos-Velasco P, et al. Predictors of Quality of Life and Other Patient-Reported Outcomes in the Panorama Multinational Study of People With Type 2 Diabetes. Diabetes Care. 2018;41(2):267-276.
  • 20. Pinto DM, Santiago LM, Maurício K, Silva IR. Health profile and medication adherence of diabetic patients in the Portuguese population. Prim Care Diabetes. 2019;13(5):446-451.
  • 21. Trief PM, Kalichman SC, Wang D, et al. Medication adherence in young adults with youth-onset type 2 diabetes: iCount, an observational study. Diabetes Res Clin Pract. 2022;184:109216.
  • 22. Diriba DC, Leung DYP, Suen LKP. Cultural Adaptation and Psychometric Properties of the Diabetes Quality of Life Scale in Afaan Oromoo among People Living with Type 2 Diabetes in Ethiopia. International Journal of Environmental Research and Public Health. 2021;18(14):16.
  • 23. Rwegerera GM, Moshomo T, Gaenamong M, et al. Health-related quality of life and associated factors among patients with diabetes mellitus in Botswana. Alexandria Journal of Medicine. 2018;54(2):111-118.
  • 24. Papadopoulos AA, Kontodimopoulos N, Frydas A, Ikonomakis E, Niakas D. Predictors of health-related quality of life in type II diabetic patients in Greece. BMC Public Health. 2007;7(1):186.
  • 25. A S, Koppad R, Sv C, Revathy R. Quality of life of type 2 diabetes patients in a tertiary care hospital in southern part of India, Shimoga, Karnataka: a cross-sectional study. International Journal of Community Medicine and Public Health. 2016;3(7):1723-1728.
  • 26. Timar R, Velea I, Timar B, et al. Factors influencing the quality of life perception in patients with type 2 diabetes mellitus. Patient Prefer Adherence. 2016;10:2471-2477.
  • 27. Akyol Güner T, Günter T. Diyabetli Bireylerde Beslenme Okuryazarlığının Yaşam Kalitesi ve Metabolik Kontrol Üzerine Etkisi. Online Turkish Journal of Health Sciences (OTJHS). 2022;7(1).
  • 28. Thomas Z, Mathew A, Jowil G, et al. Quality of life among those with diabetes mellitus type II attending a secondary outpatient facility in South India. Journal of Family Medicine and Primary Care. 2022;11(11):7204.
  • 29. Yumın ET, Bakar Y, Şimşek TT. Tip 2 Diyabeti Olan Hastalarda Diyabetin Yaşam Kalitesi Üzerine Etkisi. Turkiye Klinikleri Journal of Sports Sciences. 2017;9(2).
  • 30. Majeed A, Rehman M, Hussain I, et al. The Impact of Treatment Adherence on Quality of Life Among Type 2 Diabetes Mellitus Patients - Findings from a Cross-Sectional Study. Patient Prefer Adherence. 2021;15:475-481.
  • 31. Honish A, Westerfield W, Ashby A, Momin S, Phillippi R. Health-related quality of life and treatment compliance with diabetes care. Dis Manag. 2006;9(4):195-200.
  • 32. Perwitasari DA, Urbayatun S. Treatment Adherence and Quality of Life in Diabetes Mellitus Patients in Indonesia. SAGE Open. 2016;6(2):1-7.
Toplam 32 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Konular Aile Hekimliği
Bölüm Orijinal Makaleler
Yazarlar

Ramazan Alçınar 0000-0002-8072-1355

Mustafa Kürşat Şahin 0000-0002-3490-6009

Erken Görünüm Tarihi 16 Eylül 2023
Yayımlanma Tarihi 20 Eylül 2023
Gönderilme Tarihi 12 Haziran 2023
Yayımlandığı Sayı Yıl 2023 Cilt: 17 Sayı: 3 - Turkish Journal of Family Medicine and Primary Care

Kaynak Göster

Vancouver Alçınar R, Şahin MK. The association between medication adherence and quality of life in patients with diabetes receiving primary healthcare centers: A cross-sectional study. TJFMPC. 2023;17(3):360-9.

Sağlığın ve birinci basamak bakımın anlaşılmasına ve geliştirilmesine katkıda bulunacak yeni bilgilere sahip yazarların İngilizce veya Türkçe makaleleri memnuniyetle karşılanmaktadır.