Review
BibTex RIS Cite

Kardiyovasküler Hastalıklar ve Fonksiyonel Besinler

Year 2024, , 87 - 97, 30.04.2024

Bahar Yalçın , Melike Nur Özen

https://doi.org/10.51754/cusbed.1398809

Abstract

Kardiyovasküler hastalıklar (KVH), inme, kalp yetmezliği, hipertansiyon, romatizmal kalp hastalığı, periferik arter hastalığı gibi birçok hastalığı kapsayan günümüzde en sık görülen ve en büyük mortalite sebebi olan hastalık grubudur. KVH'lerin nedenleri arasında sigara kullanımı, fiziksel inaktivite, obezite, hiperlipidemi ve diyabet bulunsa da beslenme planı önemli bir etkendir. Fonksiyonel besinlerin KVH’lerin tedavisi ve önlenmesi için beslenme planında yer alması gerektiği düşünülmüş ve bu yönde araştırmalar yapılmıştır. Araştırmalar, fonksiyonel besinlerin kan lipid seviyelerini düşürme, plak oluşumunu azaltma, antioksidan etkileri ile arteriyel sağlığı iyileştirme ve trombosit agregasyonunu engelleme gibi mekanizmalarla KVH'ler üzerinde olumlu etkileri olduğunu göstermektedir. Ayrıca, bu besinler kanser, hipertansiyon ve astım gibi diğer kronik hastalıkların tedavisinde de kullanılmaktadır. Sonuç olarak, fonksiyonel besinlerin sağlıklı bir beslenme planına dahil edilmesi, kardiyovasküler risk faktörlerini azaltmada etkili bir yaklaşım olabilir. Bu derleme, farklı fonksiyonel besinlerin KVH riskini azaltma ve tedavi etme konusundaki etkinliğini destekleyen klinik bulguları özetlemektedir.

Keywords

kardiyovasküler fonksiyonel besinler beslenme sağlık

References

  • Abedini, M., Ghasemi-Tehrani, H., Tarrahi, M. J., & Amani, R. (2021). The effect of concentrated pomegranate juice consumption on risk factors of cardiovascular diseases in women with polycystic ovary syndrome: A randomized controlled trial. Phytotherapy Research, 35(1), 442–451. https://doi.org/10.1002/ptr.6820
  • Abeysekara, S., Chilibeck, P. D., Vatanparast, H., & Zello, G. A. (2012). A pulse-based diet is effective for reducing total and LDL-cholesterol in older adults. The British Journal of Nutrition, 108(1), S103–S110. https://doi.org/10.1017/S0007114512000748
  • Aguirre, R., & May, J. M. (2008). Inflammation in the vascular bed: importance of vitamin C. Pharmacology & Therapeutics, 119(1), 96–103. https://doi.org/10.1016/j.pharmthera.2008.05.002
  • Alasalvar, C., Salvadó, J. S., & Ros, E. (2020). Bioactives and health benefits of nuts and dried fruits. Food Chemistry, 314, 126192. https://doi.org/10.1016/j.foodchem.2020.126192
  • Alissa, E. M., Ferns, & G. A. (2012). Functional foods and nutraceuticals in the primary prevention of cardiovascular diseases. Journal of Nutrition and Metabolism, 2012, 569486. https://doi.org/10.1155/2012/569486
  • Alkerwi, A., Sauvageot, N., Crichton, G. E., Elias, M. F., & Stranges, S. (2016). Daily chocolate consumption is inversely associated with insulin resistance and liver enzymes in the Observation of Cardiovascular Risk Factors in Luxembourg study. The British Journal of Nutrition, 115(9), 1661–1668. https://doi.org/10.1017/S0007114516000702
  • Amini, M., Zayeri, F., & Salehi, M. (2021). Trend analysis of cardiovascular disease mortality, incidence, and mortality-to-incidence ratio: results from global burden of disease study 2017. BMC Public Health, 21(1), 1-12. Arnesen, E. K., Thorisdottir, B., Bärebring, L., Söderlund, F., Nwaru, B. I., Spielau, U., Dierkes, J., Ramel, A., Lamberg-
  • Allardt, C., & Åkesson, A. (2023). Nuts and seeds consumption and risk of cardiovascular disease, type 2 diabetes and their risk factors: a systematic review and meta-analysis. Food & nutrition research, 67, 10.29219/fnr.v67.8961. https://doi.org/10.29219/fnr.v67.8961
  • Askari, M., Daneshzad, E., Jafari, A., Bellissimo, N., & Azadbakht, L. (2021). Association of nut and legume consumption with Framingham 10 year risk of general cardiovascular disease in older adult men: A cross-sectional study. Clinical Nutrition ESPEN, 42, 373–380. https://doi.org/10.1016/j.clnesp.2020.12.024
  • Baeradeh, N., Ghoddusi Johari, M., Moftakhar, L., Rezaeianzadeh, R., Hosseini, S. V., & Rezaianzadeh, A. (2022). The prevalence and predictors of cardiovascular diseases in Kherameh cohort study: a population-based study on 10,663 people in southern Iran. BMC cardiovascular disorders, 22(1), 244. https://doi.org/10.1186/s12872-022-02683-w
  • Biniaz, V., Sadeghi Shermeh, M., Ebadi, A., Tayebi, A., & Einollahi, B. (2013). Effect of vitamin c supplementation on c-reactive protein levels in patients undergoing hemodialysis: a randomized, double blind, placebo-controlled study. Nephrourology Monthly, 6(1), e13351. https://doi.org/10.5812/numonthly.13351
  • Broekmans, W. M., Klöpping-Ketelaars, I. A., Schuurman, C. R., Verhagen, H., van den Berg, H., Kok, F. J., & van Poppel, G. (2000). Fruits and vegetables increase plasma carotenoids and vitamins and decrease homocysteine in humans. The Journal of Nutrition, 130(6), 1578–1583. https://doi.org/10.1093/jn/130.6.1578
  • Cao, S. Y., Zhao, C. N., Gan, R. Y., Xu, X. Y., Wei, X. L., Corke, H., & Li, H. B. (2019). Effects and mechanisms of tea and its bioactive compounds for the prevention and treatment of cardiovascular diseases: An updated review. Antioxidants, 8(6), 166. https://doi.org/10.3390/antiox8060166
  • Casas, R., Castro-Barquero, S., Estruch, R., & Sacanella, E. (2018). Nutrition and cardiovascular health. International Journal of Molecular Sciences, 19(12), 3988. https://doi.org/10.3390/ijms19123988
  • Cassidy, A., Bertoia, M., Chiuve, S., Flint, A., Forman, J., & Rimm, E. B. (2016). Habitual intake of anthocyanins and flavanones and risk of cardiovascular disease in men. The American Journal of Clinical Nutrition, 104(3), 587–594. https://doi.org/10.3945/ajcn.116.133132
  • Cheng, H. M., Koutsidis, G., Lodge, J. K., Ashor, A. W., Siervo, M., & Lara, J. (2019). Lycopene and tomato and risk of cardiovascular diseases: A systematic review and meta-analysis of epidemiological evidence. Critical Reviews in Food Science and Nutrition, 59(1), 141–158. https://doi.org/10.1080/10408398.2017.1362630
  • Chiu, H.-F., Shen, Y.-C., Venkatakrishnan, K., & Wang, C.-K. (2018). Popular functional foods and nutraceuticals with lipid lowering activity and in relation to cardiovascular disease, dyslipidemia, and related complications: an overview. Journal of Food Bioactives, 2(2), 16–27. https://doi.org/10.31665/JFB.2018.2137
  • Corti, R., Flammer, A. J., Hollenberg, N. K., & Lüscher, T. F. (2009). Cocoa and cardiovascular health. Circulation, 119(10), 1433-1441. https://doi.org/10.1161/CIRCULATIONAHA.108.827022
  • de Souza, R. J., Dehghan, M., Mente, A., Bangdiwala, S. I., Ahmed, S. H., Alhabib, K. F., Altuntas, Y., Basiak-Rasała, A., Dagenais, G. R., Diaz, R., Amma, L. I., Kelishadi, R., Khatib, R., Lear, S. A., Lopez-Jaramillo, P., Mohan, V., Poirier, P., Rangarajan, S., Rosengren, A., & Ismail, R., PURE study investigators (2020). Association of nut intake with risk factors, cardiovascular disease, and mortality in 16 countries from 5 continents: analysis from the Prospective Urban and Rural Epidemiology (PURE) study. The American Journal of Clinical Nutrition, 112(1), 208–219. https://doi.org/10.1093/ajcn/nqaa108
  • Dong, C., Bu, X., Liu, J., Wei, L., Ma, A., & Wang, T. (2022). Cardiovascular disease burden attributable to dietary risk factors from 1990 to 2019: A systematic analysis of the Global Burden of Disease study. Nutrition, Metabolism and Cardiovascular Diseases, 32(4), 897-907. https://doi.org/10.1016/j.numecd.2021.11.012
  • Edward Mashau, M., & Eugenia Ramashia, S. (2021). Role of functional food in treating and preventing cardiovascular diseases. IntechOpen. http://dx.doi.org/10.5772/intechopen.96614
  • Erdoğan Bayram, S., Özeker, E., Elmacı, Ö. L. (2013). Fonksiyonel Besinlar ve Çilek. Akademik Besin, 11 (2), 131-137. Espinoza, T., Valencia, E., Albarrán, M., Díaz, D., Quevedo, R. A., Díaz, O., & Bastías, J. (2020). Garlic (Allium sativum L) and Its beneficial properties for health: A review. Agroindustrial Science, 10(1), 103-115.
  • Essa, M. M., Bishir, M., Bhat, A., Chidambaram, S. B., Al-Balushi, B., Hamdan, H., Govindarajan, N., Freidland, R. P., & Qoronfleh, M. W. (2023). Functional foods and their impact on health. Journal of Food Science and Technology, 60(3), 820–834. https://doi.org/10.1007/s13197-021-05193-3
  • Francula-Zaninovic, S., & Nola, I. A. (2018). Management of measurable variable cardiovascular disease' risk factors. Current Cardiology Reviews, 14(3), 153-163. https://doi.org/10.2174/1573403X14666180222102312
  • Fernandes, A. S., Ferreira-Pêgo, C., & Costa, J. G. (2023). Functional Foods for Health: The Antioxidant and Anti-Inflammatory Role of Fruits, Vegetables and Culinary Herbs. Foods, 12(14), 2742.
  • García-López, S., Villanueva Arriaga, R. E., Nájera Medina, O., Rodríguez López, C. P., Figueroa-Valverde, L., Cervera, E. G., Muñozcano Skidmore, O., & Rosas-Nexticapa, M. (2016). One month of omega-3 fatty acid supplementation improves lipid profiles, glucose levels and blood pressure in overweight schoolchildren with metabolic syndrome. Journal of Pediatric Endocrinology & Metabolism : JPEM, 29(10), 1143–1150. https://doi.org/10.1515/jpem-2015-0324
  • Gianfredi, V., Salvatori, T., Nucci, D., Villarini, M., & Moretti, M. (2018). Can chocolate consumption reduce cardio-cerebrovascular risk? A systematic review and meta-analysis. Nutrition, 46, 103–114. https://doi.org/10.1016/j.nut.2017.09.006
  • Glenn, A. J., Aune, D., Freisling, H., Mohammadifard, N., Kendall, C. W. C., Salas-Salvadó, J., Jenkins, D. J. A., Hu, F. B., & Sievenpiper, J. L. (2023). Nuts and cardiovascular disease outcomes: a review of the evidence and future directions. Nutrients, 15(4), 911. https://doi.org/10.3390/nu15040911
  • Gul, K., Singh, A. K., & Jabeen, R. (2016). Nutraceuticals and Functional Foods: The Foods for the Future World. Critical Reviews in Food Science and Nutrition, 56(16), 2617–2627. https://doi.org/10.1080/10408398.2014.903384
  • Hartley, M., Fyfe, C. L., Wareham, N. J., Khaw, K. T., Johnstone, A. M., & Myint, P. K. (2022). Association between legume consumption and risk of hypertension in the european prospective ınvestigation into cancer and nutrition (EPIC)-norfolk cohort. Nutrients, 14(16), 3363. https://doi.org/10.3390/nu14163363
  • Hasan, D. S., Arief, Y. S., & Sangadji, S. S. (2023). Functional Foods and Their Implications for Health Promotion. Journal of Nutrition Education and Behavior, 55(10), 769-770.
  • Henry, C. J. (2010). Functional foods. European Journal of Clinical Nutrition, 64(7), 657-659. Hou, Y. Y., Ojo, O., Wang, L. L., Wang, Q., Jiang, Q., Shao, X. Y., & Wang, X. H. (2018). A randomized controlled trial to compare the effect of peanuts and almonds on the cardio-metabolic and ınflammatory parameters in patients with type 2 diabetes mellitus. Nutrients, 10(11), 1565. https://doi.org/10.3390/nu10111565 Ikeda, A., Iso, H., Yamagishi, K., Iwasaki, M., Yamaji, T., Miura, T., Sawada, N., Inoue, M., & Tsugane, S., JPHC Study
  • Group (2018). Plasma tea catechins and risk of cardiovascular disease in middle-aged Japanese subjects: The JPHC study. Atherosclerosis, 277, 90–97. https://doi.org/10.1016/j.atherosclerosis.2018.08.001
  • Im, J., & Park, K. (2021). Association between soy food and dietary soy ısoflavone ıntake and the risk of cardiovascular disease in women: a prospective cohort study in korea. Nutrients, 13(5), 1407. https://doi.org/10.3390/nu13051407
  • Izadi, A., Khedmat, L., Tavakolizadeh, R., & Mojtahedi, S. Y. (2020). The intake assessment of diverse dietary patterns on childhood hypertension: alleviating the blood pressure and lipidemic factors with low-sodium seafood rich in omega-3 fatty acids. Lipids in Health and Disease, 19(1), 65. https://doi.org/10.1186/s12944-020-01245-3
  • Jafari Azad, B., Daneshzad, E., & Azadbakht, L. (2020). Peanut and cardiovascular disease risk factors: A systematic review and meta-analysis. Critical Reviews in Food Science and Nutrition, 60(7), 1123–1140. https://doi.org/10.1080/10408398.2018.1558395
  • Jalilpiran, Y., Mofrad, M. D., Mozaffari, H., Bellissimo, N., & Azadbakht, L. (2020). Adherence to dietary approaches to stop hypertension (DASH) and Mediterranean dietary patterns in relation to cardiovascular risk factors in older adults. Clinical nutrition ESPEN, 39, 87-95.
  • Jędrusek-Golińska, A., Górecka, D., Buchowski, M., Wieczorowska-Tobis, K., Gramza-Michałowska, A., & Szymandera-Buszka, K. (2020). Recent progress in the use of functional foods for older adults: A narrative review. Comprehensive Reviews in Food Science and Food Safety, 19(2), 835–856. https://doi.org/10.1111/1541-4337.12530
  • Karlsen, A., Svendsen, M., Seljeflot, I., Laake, P., Duttaroy, A. K., Drevon, C. A., Arnesen, H., Tonstad, S., & Blomhoff, R. (2013). Kiwifruit decreases blood pressure and whole-blood platelet aggregation in male smokers. Journal of Human Hypertension, 27(2), 126–130. https://doi.org/10.1038/jhh.2011.116
  • Kasliwal, R. R., Bansal, M., Mehrotra, R., Yeptho, K. P., & Trehan, N. (2015). Effect of pistachio nut consumption on endothelial function and arterial stiffness. Nutrition, 31(5), 678–685. https://doi.org/10.1016/j.nut.2014.10.019
  • Khan, S. U., Lone, A. N., Khan, M. S., Virani, S. S., Blumenthal, R. S., Nasir, K., Miller, M., Michos, E. D., Ballantyne, C. M., Boden, W. E., & Bhatt, D. L. (2021). Effect of omega-3 fatty acids on cardiovascular outcomes: A systematic review and meta-analysis. Clinical Medicine, 38, 100997. https://doi.org/10.1016/j.eclinm.2021.100997
  • Konstantinidi, M., & Koutelidakis, A. E. (2019). Functional foods and bioactive compounds: A review of its possible role on weight management and obesity’s metabolic consequences. Medicines, 6(3), 94. https://doi.org/10.3390/medicines6030094
  • Laight, D. (2021). Can fish oils help to prevent cardiovascular disease? Prescriber. 32(7). 21-25. https://doi.org/10.1002/psb.1932
  • Lau, S., Georgousopoulou, E., Kellett, J., Thomas, J., Mckune, A., Mellor, D., Roach, P., & Naumovski, N. (2016). The effect of dietary supplementation of green tea catechins on cardiovascular disease risk markers in humans: a systematic review of clinical trials. Beverages, 2, 1-15. 10.3390/beverages2020016.
  • Lee-Bravatti, M. A., Wang, J., Avendano, E. E., King, L., Johnson, E. J., & Raman, G. (2019). Almond consumption and risk factors for cardiovascular disease: a systematic review and meta-analysis of randomized controlled trials. Advances in Nutrition (Bethesda, Md.), 10(6), 1076–1088. https://doi.org/10.1093/advances/nmz043.
  • Leslie, M. A., Cohen, D. J., Liddle, D. M., Robinson, L. E., & Ma, D. W. (2015). A review of the effect of omega-3 polyunsaturated fatty acids on blood triacylglycerol levels in normolipidemic and borderline hyperlipidemic individuals. Lipids in Health and Disease, 14, 53. https://doi.org/10.1186/s12944-015-0049-7
  • Li, S. H., Zhao, P., Tian, H. B., Chen, L. H., & Cui, L. Q. (2015). Effect of grape polyphenols on blood pressure: a meta-analysis of randomized controlled trials. PloS one, 10(9), e0137665. https://doi.org/10.1371/journal.pone.0137665
  • Li, Z. H., Zhong, W. F., Liu, S., Kraus, V. B., Zhang, Y. J., Gao, X., Lv, Y. B., Shen, D., Zhang, X. R., Zhang, P. D., Huang, Q. M., Chen, Q., Wu, X. B., Shi, X. M., Wang, D., & Mao, C. (2020). Associations of habitual fish oil supplementation with cardiovascular outcomes and all cause mortality: evidence from a large population based cohort study. BMJ (Clinical research ed.), 368, m456. https://doi.org/10.1136/bmj.m456
  • Liao, J., Xiong, Q., Yin, Y., Ling, Z., & Chen, S. (2022). The effects of fish oil on cardiovascular diseases: systematical evaluation and recent advance. Frontiers in Cardiovascular Medicine, 8, 802306. https://doi.org/10.3389/fcvm.2021.802306
  • Majeed, U., Shafi, A., Majeed, H., Akram, K., Liu, X., Ye, J., & Luo, Y. (2022). Grape (Vitis vinifera L.) phytochemicals and their biochemical protective mechanisms against leading pathologies. Food Chemistry, 134762. https://doi.org/10.1016/j.foodchem.2022.134762
  • Manach, C., Milenkovic, D., Van de Wiele, T., Rodriguez‐Mateos, A., de Roos, B., Garcia‐Conesa, M. T., & Morand, C. (2017). Addressing the inter‐individual variation in response to consumption of plant food bioactives: towards a better understanding of their role in healthy aging and cardiometabolic risk reduction. Molecular Nutrition & Food Research, 61(6), 1600557. https://doi.org/10.1002/mnfr.201600557
  • Mendes, V., Niforou, A., Kasdagli, M. I., Ververis, E., Naska, A. (2023). Intake of legumes and cardiovascular disease: A systematic review and dose-response meta-analysis. Nutrition, Metabolism, and Cardiovascular Diseases: NMCD, 33(1), 22–37. https://doi.org/10.1016/j.numecd.2022.10.006
  • Miller, P. E., Van Elswyk, M., & Alexander, D. D. (2014). Long-chain omega-3 fatty acids eicosapentaenoic acid and docosahexaenoic acid and blood pressure: a meta-analysis of randomized controlled trials. American Journal of Hypertension, 27(7), 885–896. https://doi.org/10.1093/ajh/hpu024
  • Mongirdienė, A., Liuizė, A., Karčiauskaitė, D., Mazgelytė, E., Liekis, A., & Sadauskienė, I. (2023). Relationship between oxidative stress and left ventricle markers in patients with chronic heart failure. Cells, 12(5), 803.
  • Musa-Veloso, K., Paulionis, L., Poon, T., & Lee, H. Y. (2016). The effects of almond consumption on fasting blood lipid levels: a systematic review and meta-analysis of randomised controlled trials. Journal of Nutritional Science, 5, 34. https://doi.org/10.1017/jns.2016.19
  • Mustafa, K., Ajmal, I., Naz, T., Fazili, A. B. A., Bai, X. & Song, Y. (2020). Bioactive functional foods for cardiovascular diseases. American Journal of Biochemistry and Biotechnology, 16(3), 354-369. https://doi.org/10.3844/ajbbsp.2020.354.369
  • Saito, E., Inoue, M., Sawada, N., Shimazu, T., Yamaji, T., Iwasaki, M., Sasazuki, S., Noda, M., Iso, H., & Tsugane, S., JPHC Study Group (2015). Association of green tea consumption with mortality due to all causes and major causes of death in a Japanese population: the Japan Public Health Center-based Prospective Study (JPHC Study). Annals of Epidemiology, 25(7), 512–518.e3. https://doi.org/10.1016/j.annepidem.2015.03.007
  • Samtiya, M., Aluko, R. E., & Dhewa, T. (2020). Plant food anti-nutritional factors and their reduction strategies: An overview. Food Production. Processing and Nutrition, 2 (1), 1–14. https://doi.org/10.1186/s43014-020-0020-5
  • Sanches Machado d’Almeida, K., Ronchi Spillere, S., Zuchinali, P., & Corrêa Souza, G. (2018). Mediterranean diet and other dietary patterns in primary prevention of heart failure and changes in cardiac function markers: a systematic review. Nutrients, 10(1), 58.
  • Sangouni, A. A., Alizadeh, M., Jamalzehi, A., & Parastouei, K. (2021). Effects of garlic powder supplementation on metabolic syndrome components, insulin resistance, fatty liver index, and appetite in subjects with metabolic syndrome: A randomized clinical trial. Phytotherapy Research, 35(8), 4433–4441. https://doi.org/10.1002/ptr.7146 Shaikh, S. (2022). Sources and Health Benefits of Functional Food Components. IntechOpen. doi: 10.5772/intechopen.104091
  • Shen, T., Xing, G., Zhu, J., Zhang, S., Cai, Y., Li, D., Xu, G., Xing, E., Rao, J., & Shi, R. (2017). Effects of 12-week supplementation of marine Omega-3 PUFA-based formulation Omega3Q10 in older adults with prehypertension and/or elevated blood cholesterol. Lipids in Health and Disease, 16(1), 253. https://doi.org/10.1186/s12944-017-0617-0
  • Skulas-Ray, A. C., Wilson, P. W. F., Harris, W. S., Brinton, E. A., Kris-Etherton, P. M., Richter, C. K., Jacobson, T. A., Engler, M. B., Miller, M., Robinson, J. G., Blum, C. B., Rodriguez-Leyva, D., de Ferranti, S. D., Welty, F. K., & American Heart Association Council on Arteriosclerosis, Thrombosis and Vascular Biology; Council on Lifestyle and Cardiometabolic Health; Council on Cardiovascular Disease in the Young; Council on Cardiovascular and Stroke Nursing; and Council on Clinical Cardiology (2019). Omega-3 Fatty Acids for the Management of Hypertriglyceridemia: A Science Advisory From the American Heart Association. Circulation, 140(12),e673–e691. https://doi.org/10.1161/CIR.0000000000000709
  • Stockton, A., Farhat, G., McDougall, G. J., & Al-Dujaili, E. A. S. (2017). Effect of pomegranate extract on blood pressure and anthropometry in adults: a double-blind placebo-controlled randomised clinical trial. Journal of Nutritional Science, 6, (39). https://doi.org/10.1017/jns.2017.36
  • Sun, Y., Liu, B., Snetselaar, L. G., Wallace, R. B., Shadyab, A. H., Chen, G. C., Shikany, J. M., Manson, J. E., & Bao, W. (2023). Chocolate consumption in relation to all-cause and cause-specific mortality in women: the women's health initiative. Journal of the Academy of Nutrition and Dietetics, 123(6), 902–911.e3. https://doi.org/10.1016/j.jand.2022.12.007
  • Svendsen, M., Tonstad, S., Heggen, E., Pedersen, T. R., Seljeflot, I., Bøhn, S. K., Bastani, N. E., Blomhoff, R., Holme, I. M., & Klemsdal, T. O. (2015). The effect of kiwifruit consumption on blood pressure in subjects with moderately elevated blood pressure: a randomized, controlled study. Blood Pressure, 24(1), 48–54. https://doi.org/10.3109/08037051.2014.976979
  • Pang, J., Zhang, Z., Zheng, T. Z., Bassig, B. A., Mao, C., Liu, X., Zhu, Y., Shi, K., Ge, J., Yang, Y. J., Dejia-Huang, Bai, M., & Peng, Y. (2016). Green tea consumption and risk of cardiovascular and ischemic related diseases: A meta-analysis. International Journal of Cardiology, 202, 967–974. https://doi.org/10.1016/j.ijcard.2014.12.176
  • Padayachee, A., Day, L., Howell, K., & Gidley, M. J. (2017). Complexity and health functionality of plant cell wall fibers from fruits and vegetables. Critical Reviews in Food Science And Nutrition, 57(1), 59-81. https://doi.org/10.1080/10408398.2013.850652
  • Peluso, I., & Serafini, M. (2017). Antioxidants from black and green tea: from dietary modulation of oxidative stress to pharmacological mechanisms. British Journal of Pharmacology, 174(11), 1195–1208. https://doi.org/10.1111/bph.13649
  • Peou, S., Milliard-Hasting, B., & Shah, S. A. (2016). Impact of avocado-enriched diets on plasma lipoproteins: A meta-analysis. Journal of Clinical Lipidology, 10(1), 161–171. https://doi.org/10.1016/j.jacl.2015.10.011
  • Popiolek-Kalisz, J., & Fornal, E. (2022). The Impact of Flavonols on Cardiovascular Risk. Nutrients, 14(9), 1973-1973. Rautiainen, S., Levitan, E. B., Mittleman, M. A., & Wolk, A. (2015). Fruit and vegetable intake and rate of heart failure: a population-based prospective cohort of women. European Journal of Heart Failure, 17(1), 20–26. https://doi.org/10.1002/ejhf.191
  • Ren, Y., Liu, Y., Sun, X. Z., Wang, B. Y., Zhao, Y., Liu, D. C., Zhang, D. D., Liu, X. J., Zhang, R. Y., Sun, H. H., Liu, F. Y., Chen, X., Cheng, C., Liu, L. L., Zhou, Q. G., Zhang, M., & Hu, D. S. (2019). Chocolate consumption and risk of cardiovascular diseases: a meta-analysis of prospective studies. Heart (British Cardiac Society), 105(1), 49–55. https://doi.org/10.1136/heartjnl-2018-313131
  • Tan, B. L., & Norhaizan, M. E. (2019). Carotenoids: how effective are they to prevent age-related diseases? Molecules, 24(9), 1801. https://doi.org/10.3390/molecules24091801
  • Tenore, G. C., Caruso, D., Buonomo, G., D'Urso, E., D'Avino, M., Campiglia, P., Marinelli, L., & Novellino, E. (2017). Annurca (Malus pumila Miller cv. Annurca) apple as a functional food for the contribution to a healthy balance of plasma cholesterol levels: results of a randomized clinical trial. Journal of the Science of Food and Agriculture, 97(7), 2107–2115. https://doi.org/10.1002/jsfa.8016
  • Tian, C., Huang, Q., Yang, L., Légaré, S., Angileri, F., Yang, H., Li, X., Min, X., Zhang, C., Xu, C., Yuan, J., Miao, X., He, M. A., Wu, T., & Zhang, X. (2016). Green tea consumption is associated with reduced incident CHD and improved CHD-related biomarkers in the Dongfeng-Tongji cohort. Scientific Reports, 6, 24353. https://doi.org/10.1038/srep24353
  • Van Camp, G. (2014). Cardiovascular disease prevention. Acta Clinica Belgica, 69(6), 407-411. Vučić, V., Grabež, M., Trchounian, A., & Arsić, A. (2019). Composition and potential health benefits of pomegranate: a review. Current Pharmaceutical Design, 25(16), 1817–1827. https://doi.org/10.2174/1381612825666190708183941
  • Wang, Z. M., Zhao, D., Wang, H., Wang, Q. M., Zhou, B., & Wang, L. S. (2023). Green tea consumption and the risk of coronary heart disease: A systematic review and meta-analysis of cohort studies. Nutrition, Metabolism, and Cardiovascular Diseases : NMCD, 33(4), 715–723. https://doi.org/10.1016/j.numecd.2023.01.017
  • Wang, X., Liu, F., Li, J., Yang, X., Chen, J., Cao, J., Wu, X., Lu, X., Huang, J., Li, Y., Zhao, L., Shen, C., Hu, D., Yu, L., Liu, X., Wu, X., Wu, S., & Gu, D. (2020). Tea consumption and the risk of atherosclerotic cardiovascular disease and all-cause mortality: The China-PAR project. European Journal of Preventive Cardiology, 27(18), 1956–1963. https://doi.org/10.1177/2047487319894685
  • Weylandt, K. H., Serini, S., Chen, Y. Q., Su, H. M., Lim, K., Cittadini, A., & Calviello, G. (2015). Omega-3 polyunsaturated fatty acids: the way forward in times of mixed evidence. BioMed Research International, 2015, 143109. https://doi.org/10.1155/2015/143109
  • Xu, C., Mathews, A. E., Rodrigues, C., Eudy, B. J., Rowe, C. A., O'Donoughue, A., & Percival, S. S. (2018). Aged garlic extract supplementation modifies inflammation and immunity of adults with obesity: A randomized, double-blind, placebo-controlled clinical trial. Clinical Nutrition ESPEN, 24, 148–155. https://doi.org/10.1016/j.clnesp.2017.11.010
  • Xu, R., Yang, K., Ding, J., & Chen, G. (2020). Effect of green tea supplementation on blood pressure: A systematic review and meta-analysis of randomized controlled trials. Medicine, 99(6), e19047. https://doi.org/10.1097/MD.0000000000019047
  • Yang, J., Zhou, J., Yang, J., Lou, H., Zhao, B., Chi, J., & Guo, H. (2023). Dark chocolate ıntake and cardiovascular diseases: a mendelian randomization study. Research Squary, (1). https://doi.org/10.21203/rs.3.rs-2919868/v1 Yi, S. Y., Steffen, L. M., Zhou, X., Shikany, J. M., & Jacobs, D. R., Jr (2022). Association of nut consumption with CVD risk factors in young to middle-aged adults: The Coronary Artery Risk Development in Young Adults (CARDIA) study. Nutrition, metabolism and cardiovascular disease: NMCD, 32(10), 2321-2329. https://doi.org/10.1016/j.numecd.2022.07.013
  • Yilmaz, M. I., Romano, M., Basarali, M. K., Elzagallaai, A., Karaman, M., Demir, Z., Demir, M. F., Akcay, F., Seyrek, M., Haksever, N., Piskin, D., Cimaz, R., Rieder, M. J., & Demirkaya, E. (2020). The Effect of Corrected Inflammation, Oxidative Stress and Endothelial Dysfunction on Fmd Levels in Patients with Selected Chronic Diseases: A Quasi-Experimental Study. Scientific reports, 10(1), 9018. https://doi.org/10.1038/s41598-020-65528-6

Cardiovascular Diseases and Functional Foods

Year 2024, , 87 - 97, 30.04.2024

Bahar Yalçın , Melike Nur Özen

https://doi.org/10.51754/cusbed.1398809

Abstract

Cardiovascular diseases (CVDs), including stroke, heart failure, hypertension, rheumatic heart disease, hypertension, rheumatic heart disease and peripheral arterial disease, are the most common and the leading cause of mortality. Although the causes of CVDs include smoking, physical inactivity, obesity, hyperlipidemia and diabetes, nutrition plan is an important factor. It was thought that functional foods should be included in the nutrition plan for the treatment and prevention of CVDs, and studies were conducted in this direction. Studies show that functional foods have positive effects on CVDs through mechanisms such as lowering blood lipid levels, reducing plaque formation, improving arterial health with antioxidant effects, and inhibiting platelet aggregation. In addition, these foods are also used in the treatment of other chronic diseases such as cancer, hypertension and asthma. In conclusion, the inclusion of functional foods in a healthy eating plan may be an effective approach to reduce cardiovascular risk factors. This review summarizes the results of clinical studies that support the effectiveness of various functional foods in reducing and treating CVD risk.

Keywords

Cardiovascular functional foods nutrition health

References

  • Abedini, M., Ghasemi-Tehrani, H., Tarrahi, M. J., & Amani, R. (2021). The effect of concentrated pomegranate juice consumption on risk factors of cardiovascular diseases in women with polycystic ovary syndrome: A randomized controlled trial. Phytotherapy Research, 35(1), 442–451. https://doi.org/10.1002/ptr.6820
  • Abeysekara, S., Chilibeck, P. D., Vatanparast, H., & Zello, G. A. (2012). A pulse-based diet is effective for reducing total and LDL-cholesterol in older adults. The British Journal of Nutrition, 108(1), S103–S110. https://doi.org/10.1017/S0007114512000748
  • Aguirre, R., & May, J. M. (2008). Inflammation in the vascular bed: importance of vitamin C. Pharmacology & Therapeutics, 119(1), 96–103. https://doi.org/10.1016/j.pharmthera.2008.05.002
  • Alasalvar, C., Salvadó, J. S., & Ros, E. (2020). Bioactives and health benefits of nuts and dried fruits. Food Chemistry, 314, 126192. https://doi.org/10.1016/j.foodchem.2020.126192
  • Alissa, E. M., Ferns, & G. A. (2012). Functional foods and nutraceuticals in the primary prevention of cardiovascular diseases. Journal of Nutrition and Metabolism, 2012, 569486. https://doi.org/10.1155/2012/569486
  • Alkerwi, A., Sauvageot, N., Crichton, G. E., Elias, M. F., & Stranges, S. (2016). Daily chocolate consumption is inversely associated with insulin resistance and liver enzymes in the Observation of Cardiovascular Risk Factors in Luxembourg study. The British Journal of Nutrition, 115(9), 1661–1668. https://doi.org/10.1017/S0007114516000702
  • Amini, M., Zayeri, F., & Salehi, M. (2021). Trend analysis of cardiovascular disease mortality, incidence, and mortality-to-incidence ratio: results from global burden of disease study 2017. BMC Public Health, 21(1), 1-12. Arnesen, E. K., Thorisdottir, B., Bärebring, L., Söderlund, F., Nwaru, B. I., Spielau, U., Dierkes, J., Ramel, A., Lamberg-
  • Allardt, C., & Åkesson, A. (2023). Nuts and seeds consumption and risk of cardiovascular disease, type 2 diabetes and their risk factors: a systematic review and meta-analysis. Food & nutrition research, 67, 10.29219/fnr.v67.8961. https://doi.org/10.29219/fnr.v67.8961
  • Askari, M., Daneshzad, E., Jafari, A., Bellissimo, N., & Azadbakht, L. (2021). Association of nut and legume consumption with Framingham 10 year risk of general cardiovascular disease in older adult men: A cross-sectional study. Clinical Nutrition ESPEN, 42, 373–380. https://doi.org/10.1016/j.clnesp.2020.12.024
  • Baeradeh, N., Ghoddusi Johari, M., Moftakhar, L., Rezaeianzadeh, R., Hosseini, S. V., & Rezaianzadeh, A. (2022). The prevalence and predictors of cardiovascular diseases in Kherameh cohort study: a population-based study on 10,663 people in southern Iran. BMC cardiovascular disorders, 22(1), 244. https://doi.org/10.1186/s12872-022-02683-w
  • Biniaz, V., Sadeghi Shermeh, M., Ebadi, A., Tayebi, A., & Einollahi, B. (2013). Effect of vitamin c supplementation on c-reactive protein levels in patients undergoing hemodialysis: a randomized, double blind, placebo-controlled study. Nephrourology Monthly, 6(1), e13351. https://doi.org/10.5812/numonthly.13351
  • Broekmans, W. M., Klöpping-Ketelaars, I. A., Schuurman, C. R., Verhagen, H., van den Berg, H., Kok, F. J., & van Poppel, G. (2000). Fruits and vegetables increase plasma carotenoids and vitamins and decrease homocysteine in humans. The Journal of Nutrition, 130(6), 1578–1583. https://doi.org/10.1093/jn/130.6.1578
  • Cao, S. Y., Zhao, C. N., Gan, R. Y., Xu, X. Y., Wei, X. L., Corke, H., & Li, H. B. (2019). Effects and mechanisms of tea and its bioactive compounds for the prevention and treatment of cardiovascular diseases: An updated review. Antioxidants, 8(6), 166. https://doi.org/10.3390/antiox8060166
  • Casas, R., Castro-Barquero, S., Estruch, R., & Sacanella, E. (2018). Nutrition and cardiovascular health. International Journal of Molecular Sciences, 19(12), 3988. https://doi.org/10.3390/ijms19123988
  • Cassidy, A., Bertoia, M., Chiuve, S., Flint, A., Forman, J., & Rimm, E. B. (2016). Habitual intake of anthocyanins and flavanones and risk of cardiovascular disease in men. The American Journal of Clinical Nutrition, 104(3), 587–594. https://doi.org/10.3945/ajcn.116.133132
  • Cheng, H. M., Koutsidis, G., Lodge, J. K., Ashor, A. W., Siervo, M., & Lara, J. (2019). Lycopene and tomato and risk of cardiovascular diseases: A systematic review and meta-analysis of epidemiological evidence. Critical Reviews in Food Science and Nutrition, 59(1), 141–158. https://doi.org/10.1080/10408398.2017.1362630
  • Chiu, H.-F., Shen, Y.-C., Venkatakrishnan, K., & Wang, C.-K. (2018). Popular functional foods and nutraceuticals with lipid lowering activity and in relation to cardiovascular disease, dyslipidemia, and related complications: an overview. Journal of Food Bioactives, 2(2), 16–27. https://doi.org/10.31665/JFB.2018.2137
  • Corti, R., Flammer, A. J., Hollenberg, N. K., & Lüscher, T. F. (2009). Cocoa and cardiovascular health. Circulation, 119(10), 1433-1441. https://doi.org/10.1161/CIRCULATIONAHA.108.827022
  • de Souza, R. J., Dehghan, M., Mente, A., Bangdiwala, S. I., Ahmed, S. H., Alhabib, K. F., Altuntas, Y., Basiak-Rasała, A., Dagenais, G. R., Diaz, R., Amma, L. I., Kelishadi, R., Khatib, R., Lear, S. A., Lopez-Jaramillo, P., Mohan, V., Poirier, P., Rangarajan, S., Rosengren, A., & Ismail, R., PURE study investigators (2020). Association of nut intake with risk factors, cardiovascular disease, and mortality in 16 countries from 5 continents: analysis from the Prospective Urban and Rural Epidemiology (PURE) study. The American Journal of Clinical Nutrition, 112(1), 208–219. https://doi.org/10.1093/ajcn/nqaa108
  • Dong, C., Bu, X., Liu, J., Wei, L., Ma, A., & Wang, T. (2022). Cardiovascular disease burden attributable to dietary risk factors from 1990 to 2019: A systematic analysis of the Global Burden of Disease study. Nutrition, Metabolism and Cardiovascular Diseases, 32(4), 897-907. https://doi.org/10.1016/j.numecd.2021.11.012
  • Edward Mashau, M., & Eugenia Ramashia, S. (2021). Role of functional food in treating and preventing cardiovascular diseases. IntechOpen. http://dx.doi.org/10.5772/intechopen.96614
  • Erdoğan Bayram, S., Özeker, E., Elmacı, Ö. L. (2013). Fonksiyonel Besinlar ve Çilek. Akademik Besin, 11 (2), 131-137. Espinoza, T., Valencia, E., Albarrán, M., Díaz, D., Quevedo, R. A., Díaz, O., & Bastías, J. (2020). Garlic (Allium sativum L) and Its beneficial properties for health: A review. Agroindustrial Science, 10(1), 103-115.
  • Essa, M. M., Bishir, M., Bhat, A., Chidambaram, S. B., Al-Balushi, B., Hamdan, H., Govindarajan, N., Freidland, R. P., & Qoronfleh, M. W. (2023). Functional foods and their impact on health. Journal of Food Science and Technology, 60(3), 820–834. https://doi.org/10.1007/s13197-021-05193-3
  • Francula-Zaninovic, S., & Nola, I. A. (2018). Management of measurable variable cardiovascular disease' risk factors. Current Cardiology Reviews, 14(3), 153-163. https://doi.org/10.2174/1573403X14666180222102312
  • Fernandes, A. S., Ferreira-Pêgo, C., & Costa, J. G. (2023). Functional Foods for Health: The Antioxidant and Anti-Inflammatory Role of Fruits, Vegetables and Culinary Herbs. Foods, 12(14), 2742.
  • García-López, S., Villanueva Arriaga, R. E., Nájera Medina, O., Rodríguez López, C. P., Figueroa-Valverde, L., Cervera, E. G., Muñozcano Skidmore, O., & Rosas-Nexticapa, M. (2016). One month of omega-3 fatty acid supplementation improves lipid profiles, glucose levels and blood pressure in overweight schoolchildren with metabolic syndrome. Journal of Pediatric Endocrinology & Metabolism : JPEM, 29(10), 1143–1150. https://doi.org/10.1515/jpem-2015-0324
  • Gianfredi, V., Salvatori, T., Nucci, D., Villarini, M., & Moretti, M. (2018). Can chocolate consumption reduce cardio-cerebrovascular risk? A systematic review and meta-analysis. Nutrition, 46, 103–114. https://doi.org/10.1016/j.nut.2017.09.006
  • Glenn, A. J., Aune, D., Freisling, H., Mohammadifard, N., Kendall, C. W. C., Salas-Salvadó, J., Jenkins, D. J. A., Hu, F. B., & Sievenpiper, J. L. (2023). Nuts and cardiovascular disease outcomes: a review of the evidence and future directions. Nutrients, 15(4), 911. https://doi.org/10.3390/nu15040911
  • Gul, K., Singh, A. K., & Jabeen, R. (2016). Nutraceuticals and Functional Foods: The Foods for the Future World. Critical Reviews in Food Science and Nutrition, 56(16), 2617–2627. https://doi.org/10.1080/10408398.2014.903384
  • Hartley, M., Fyfe, C. L., Wareham, N. J., Khaw, K. T., Johnstone, A. M., & Myint, P. K. (2022). Association between legume consumption and risk of hypertension in the european prospective ınvestigation into cancer and nutrition (EPIC)-norfolk cohort. Nutrients, 14(16), 3363. https://doi.org/10.3390/nu14163363
  • Hasan, D. S., Arief, Y. S., & Sangadji, S. S. (2023). Functional Foods and Their Implications for Health Promotion. Journal of Nutrition Education and Behavior, 55(10), 769-770.
  • Henry, C. J. (2010). Functional foods. European Journal of Clinical Nutrition, 64(7), 657-659. Hou, Y. Y., Ojo, O., Wang, L. L., Wang, Q., Jiang, Q., Shao, X. Y., & Wang, X. H. (2018). A randomized controlled trial to compare the effect of peanuts and almonds on the cardio-metabolic and ınflammatory parameters in patients with type 2 diabetes mellitus. Nutrients, 10(11), 1565. https://doi.org/10.3390/nu10111565 Ikeda, A., Iso, H., Yamagishi, K., Iwasaki, M., Yamaji, T., Miura, T., Sawada, N., Inoue, M., & Tsugane, S., JPHC Study
  • Group (2018). Plasma tea catechins and risk of cardiovascular disease in middle-aged Japanese subjects: The JPHC study. Atherosclerosis, 277, 90–97. https://doi.org/10.1016/j.atherosclerosis.2018.08.001
  • Im, J., & Park, K. (2021). Association between soy food and dietary soy ısoflavone ıntake and the risk of cardiovascular disease in women: a prospective cohort study in korea. Nutrients, 13(5), 1407. https://doi.org/10.3390/nu13051407
  • Izadi, A., Khedmat, L., Tavakolizadeh, R., & Mojtahedi, S. Y. (2020). The intake assessment of diverse dietary patterns on childhood hypertension: alleviating the blood pressure and lipidemic factors with low-sodium seafood rich in omega-3 fatty acids. Lipids in Health and Disease, 19(1), 65. https://doi.org/10.1186/s12944-020-01245-3
  • Jafari Azad, B., Daneshzad, E., & Azadbakht, L. (2020). Peanut and cardiovascular disease risk factors: A systematic review and meta-analysis. Critical Reviews in Food Science and Nutrition, 60(7), 1123–1140. https://doi.org/10.1080/10408398.2018.1558395
  • Jalilpiran, Y., Mofrad, M. D., Mozaffari, H., Bellissimo, N., & Azadbakht, L. (2020). Adherence to dietary approaches to stop hypertension (DASH) and Mediterranean dietary patterns in relation to cardiovascular risk factors in older adults. Clinical nutrition ESPEN, 39, 87-95.
  • Jędrusek-Golińska, A., Górecka, D., Buchowski, M., Wieczorowska-Tobis, K., Gramza-Michałowska, A., & Szymandera-Buszka, K. (2020). Recent progress in the use of functional foods for older adults: A narrative review. Comprehensive Reviews in Food Science and Food Safety, 19(2), 835–856. https://doi.org/10.1111/1541-4337.12530
  • Karlsen, A., Svendsen, M., Seljeflot, I., Laake, P., Duttaroy, A. K., Drevon, C. A., Arnesen, H., Tonstad, S., & Blomhoff, R. (2013). Kiwifruit decreases blood pressure and whole-blood platelet aggregation in male smokers. Journal of Human Hypertension, 27(2), 126–130. https://doi.org/10.1038/jhh.2011.116
  • Kasliwal, R. R., Bansal, M., Mehrotra, R., Yeptho, K. P., & Trehan, N. (2015). Effect of pistachio nut consumption on endothelial function and arterial stiffness. Nutrition, 31(5), 678–685. https://doi.org/10.1016/j.nut.2014.10.019
  • Khan, S. U., Lone, A. N., Khan, M. S., Virani, S. S., Blumenthal, R. S., Nasir, K., Miller, M., Michos, E. D., Ballantyne, C. M., Boden, W. E., & Bhatt, D. L. (2021). Effect of omega-3 fatty acids on cardiovascular outcomes: A systematic review and meta-analysis. Clinical Medicine, 38, 100997. https://doi.org/10.1016/j.eclinm.2021.100997
  • Konstantinidi, M., & Koutelidakis, A. E. (2019). Functional foods and bioactive compounds: A review of its possible role on weight management and obesity’s metabolic consequences. Medicines, 6(3), 94. https://doi.org/10.3390/medicines6030094
  • Laight, D. (2021). Can fish oils help to prevent cardiovascular disease? Prescriber. 32(7). 21-25. https://doi.org/10.1002/psb.1932
  • Lau, S., Georgousopoulou, E., Kellett, J., Thomas, J., Mckune, A., Mellor, D., Roach, P., & Naumovski, N. (2016). The effect of dietary supplementation of green tea catechins on cardiovascular disease risk markers in humans: a systematic review of clinical trials. Beverages, 2, 1-15. 10.3390/beverages2020016.
  • Lee-Bravatti, M. A., Wang, J., Avendano, E. E., King, L., Johnson, E. J., & Raman, G. (2019). Almond consumption and risk factors for cardiovascular disease: a systematic review and meta-analysis of randomized controlled trials. Advances in Nutrition (Bethesda, Md.), 10(6), 1076–1088. https://doi.org/10.1093/advances/nmz043.
  • Leslie, M. A., Cohen, D. J., Liddle, D. M., Robinson, L. E., & Ma, D. W. (2015). A review of the effect of omega-3 polyunsaturated fatty acids on blood triacylglycerol levels in normolipidemic and borderline hyperlipidemic individuals. Lipids in Health and Disease, 14, 53. https://doi.org/10.1186/s12944-015-0049-7
  • Li, S. H., Zhao, P., Tian, H. B., Chen, L. H., & Cui, L. Q. (2015). Effect of grape polyphenols on blood pressure: a meta-analysis of randomized controlled trials. PloS one, 10(9), e0137665. https://doi.org/10.1371/journal.pone.0137665
  • Li, Z. H., Zhong, W. F., Liu, S., Kraus, V. B., Zhang, Y. J., Gao, X., Lv, Y. B., Shen, D., Zhang, X. R., Zhang, P. D., Huang, Q. M., Chen, Q., Wu, X. B., Shi, X. M., Wang, D., & Mao, C. (2020). Associations of habitual fish oil supplementation with cardiovascular outcomes and all cause mortality: evidence from a large population based cohort study. BMJ (Clinical research ed.), 368, m456. https://doi.org/10.1136/bmj.m456
  • Liao, J., Xiong, Q., Yin, Y., Ling, Z., & Chen, S. (2022). The effects of fish oil on cardiovascular diseases: systematical evaluation and recent advance. Frontiers in Cardiovascular Medicine, 8, 802306. https://doi.org/10.3389/fcvm.2021.802306
  • Majeed, U., Shafi, A., Majeed, H., Akram, K., Liu, X., Ye, J., & Luo, Y. (2022). Grape (Vitis vinifera L.) phytochemicals and their biochemical protective mechanisms against leading pathologies. Food Chemistry, 134762. https://doi.org/10.1016/j.foodchem.2022.134762
  • Manach, C., Milenkovic, D., Van de Wiele, T., Rodriguez‐Mateos, A., de Roos, B., Garcia‐Conesa, M. T., & Morand, C. (2017). Addressing the inter‐individual variation in response to consumption of plant food bioactives: towards a better understanding of their role in healthy aging and cardiometabolic risk reduction. Molecular Nutrition & Food Research, 61(6), 1600557. https://doi.org/10.1002/mnfr.201600557
  • Mendes, V., Niforou, A., Kasdagli, M. I., Ververis, E., Naska, A. (2023). Intake of legumes and cardiovascular disease: A systematic review and dose-response meta-analysis. Nutrition, Metabolism, and Cardiovascular Diseases: NMCD, 33(1), 22–37. https://doi.org/10.1016/j.numecd.2022.10.006
  • Miller, P. E., Van Elswyk, M., & Alexander, D. D. (2014). Long-chain omega-3 fatty acids eicosapentaenoic acid and docosahexaenoic acid and blood pressure: a meta-analysis of randomized controlled trials. American Journal of Hypertension, 27(7), 885–896. https://doi.org/10.1093/ajh/hpu024
  • Mongirdienė, A., Liuizė, A., Karčiauskaitė, D., Mazgelytė, E., Liekis, A., & Sadauskienė, I. (2023). Relationship between oxidative stress and left ventricle markers in patients with chronic heart failure. Cells, 12(5), 803.
  • Musa-Veloso, K., Paulionis, L., Poon, T., & Lee, H. Y. (2016). The effects of almond consumption on fasting blood lipid levels: a systematic review and meta-analysis of randomised controlled trials. Journal of Nutritional Science, 5, 34. https://doi.org/10.1017/jns.2016.19
  • Mustafa, K., Ajmal, I., Naz, T., Fazili, A. B. A., Bai, X. & Song, Y. (2020). Bioactive functional foods for cardiovascular diseases. American Journal of Biochemistry and Biotechnology, 16(3), 354-369. https://doi.org/10.3844/ajbbsp.2020.354.369
  • Saito, E., Inoue, M., Sawada, N., Shimazu, T., Yamaji, T., Iwasaki, M., Sasazuki, S., Noda, M., Iso, H., & Tsugane, S., JPHC Study Group (2015). Association of green tea consumption with mortality due to all causes and major causes of death in a Japanese population: the Japan Public Health Center-based Prospective Study (JPHC Study). Annals of Epidemiology, 25(7), 512–518.e3. https://doi.org/10.1016/j.annepidem.2015.03.007
  • Samtiya, M., Aluko, R. E., & Dhewa, T. (2020). Plant food anti-nutritional factors and their reduction strategies: An overview. Food Production. Processing and Nutrition, 2 (1), 1–14. https://doi.org/10.1186/s43014-020-0020-5
  • Sanches Machado d’Almeida, K., Ronchi Spillere, S., Zuchinali, P., & Corrêa Souza, G. (2018). Mediterranean diet and other dietary patterns in primary prevention of heart failure and changes in cardiac function markers: a systematic review. Nutrients, 10(1), 58.
  • Sangouni, A. A., Alizadeh, M., Jamalzehi, A., & Parastouei, K. (2021). Effects of garlic powder supplementation on metabolic syndrome components, insulin resistance, fatty liver index, and appetite in subjects with metabolic syndrome: A randomized clinical trial. Phytotherapy Research, 35(8), 4433–4441. https://doi.org/10.1002/ptr.7146 Shaikh, S. (2022). Sources and Health Benefits of Functional Food Components. IntechOpen. doi: 10.5772/intechopen.104091
  • Shen, T., Xing, G., Zhu, J., Zhang, S., Cai, Y., Li, D., Xu, G., Xing, E., Rao, J., & Shi, R. (2017). Effects of 12-week supplementation of marine Omega-3 PUFA-based formulation Omega3Q10 in older adults with prehypertension and/or elevated blood cholesterol. Lipids in Health and Disease, 16(1), 253. https://doi.org/10.1186/s12944-017-0617-0
  • Skulas-Ray, A. C., Wilson, P. W. F., Harris, W. S., Brinton, E. A., Kris-Etherton, P. M., Richter, C. K., Jacobson, T. A., Engler, M. B., Miller, M., Robinson, J. G., Blum, C. B., Rodriguez-Leyva, D., de Ferranti, S. D., Welty, F. K., & American Heart Association Council on Arteriosclerosis, Thrombosis and Vascular Biology; Council on Lifestyle and Cardiometabolic Health; Council on Cardiovascular Disease in the Young; Council on Cardiovascular and Stroke Nursing; and Council on Clinical Cardiology (2019). Omega-3 Fatty Acids for the Management of Hypertriglyceridemia: A Science Advisory From the American Heart Association. Circulation, 140(12),e673–e691. https://doi.org/10.1161/CIR.0000000000000709
  • Stockton, A., Farhat, G., McDougall, G. J., & Al-Dujaili, E. A. S. (2017). Effect of pomegranate extract on blood pressure and anthropometry in adults: a double-blind placebo-controlled randomised clinical trial. Journal of Nutritional Science, 6, (39). https://doi.org/10.1017/jns.2017.36
  • Sun, Y., Liu, B., Snetselaar, L. G., Wallace, R. B., Shadyab, A. H., Chen, G. C., Shikany, J. M., Manson, J. E., & Bao, W. (2023). Chocolate consumption in relation to all-cause and cause-specific mortality in women: the women's health initiative. Journal of the Academy of Nutrition and Dietetics, 123(6), 902–911.e3. https://doi.org/10.1016/j.jand.2022.12.007
  • Svendsen, M., Tonstad, S., Heggen, E., Pedersen, T. R., Seljeflot, I., Bøhn, S. K., Bastani, N. E., Blomhoff, R., Holme, I. M., & Klemsdal, T. O. (2015). The effect of kiwifruit consumption on blood pressure in subjects with moderately elevated blood pressure: a randomized, controlled study. Blood Pressure, 24(1), 48–54. https://doi.org/10.3109/08037051.2014.976979
  • Pang, J., Zhang, Z., Zheng, T. Z., Bassig, B. A., Mao, C., Liu, X., Zhu, Y., Shi, K., Ge, J., Yang, Y. J., Dejia-Huang, Bai, M., & Peng, Y. (2016). Green tea consumption and risk of cardiovascular and ischemic related diseases: A meta-analysis. International Journal of Cardiology, 202, 967–974. https://doi.org/10.1016/j.ijcard.2014.12.176
  • Padayachee, A., Day, L., Howell, K., & Gidley, M. J. (2017). Complexity and health functionality of plant cell wall fibers from fruits and vegetables. Critical Reviews in Food Science And Nutrition, 57(1), 59-81. https://doi.org/10.1080/10408398.2013.850652
  • Peluso, I., & Serafini, M. (2017). Antioxidants from black and green tea: from dietary modulation of oxidative stress to pharmacological mechanisms. British Journal of Pharmacology, 174(11), 1195–1208. https://doi.org/10.1111/bph.13649
  • Peou, S., Milliard-Hasting, B., & Shah, S. A. (2016). Impact of avocado-enriched diets on plasma lipoproteins: A meta-analysis. Journal of Clinical Lipidology, 10(1), 161–171. https://doi.org/10.1016/j.jacl.2015.10.011
  • Popiolek-Kalisz, J., & Fornal, E. (2022). The Impact of Flavonols on Cardiovascular Risk. Nutrients, 14(9), 1973-1973. Rautiainen, S., Levitan, E. B., Mittleman, M. A., & Wolk, A. (2015). Fruit and vegetable intake and rate of heart failure: a population-based prospective cohort of women. European Journal of Heart Failure, 17(1), 20–26. https://doi.org/10.1002/ejhf.191
  • Ren, Y., Liu, Y., Sun, X. Z., Wang, B. Y., Zhao, Y., Liu, D. C., Zhang, D. D., Liu, X. J., Zhang, R. Y., Sun, H. H., Liu, F. Y., Chen, X., Cheng, C., Liu, L. L., Zhou, Q. G., Zhang, M., & Hu, D. S. (2019). Chocolate consumption and risk of cardiovascular diseases: a meta-analysis of prospective studies. Heart (British Cardiac Society), 105(1), 49–55. https://doi.org/10.1136/heartjnl-2018-313131
  • Tan, B. L., & Norhaizan, M. E. (2019). Carotenoids: how effective are they to prevent age-related diseases? Molecules, 24(9), 1801. https://doi.org/10.3390/molecules24091801
  • Tenore, G. C., Caruso, D., Buonomo, G., D'Urso, E., D'Avino, M., Campiglia, P., Marinelli, L., & Novellino, E. (2017). Annurca (Malus pumila Miller cv. Annurca) apple as a functional food for the contribution to a healthy balance of plasma cholesterol levels: results of a randomized clinical trial. Journal of the Science of Food and Agriculture, 97(7), 2107–2115. https://doi.org/10.1002/jsfa.8016
  • Tian, C., Huang, Q., Yang, L., Légaré, S., Angileri, F., Yang, H., Li, X., Min, X., Zhang, C., Xu, C., Yuan, J., Miao, X., He, M. A., Wu, T., & Zhang, X. (2016). Green tea consumption is associated with reduced incident CHD and improved CHD-related biomarkers in the Dongfeng-Tongji cohort. Scientific Reports, 6, 24353. https://doi.org/10.1038/srep24353
  • Van Camp, G. (2014). Cardiovascular disease prevention. Acta Clinica Belgica, 69(6), 407-411. Vučić, V., Grabež, M., Trchounian, A., & Arsić, A. (2019). Composition and potential health benefits of pomegranate: a review. Current Pharmaceutical Design, 25(16), 1817–1827. https://doi.org/10.2174/1381612825666190708183941
  • Wang, Z. M., Zhao, D., Wang, H., Wang, Q. M., Zhou, B., & Wang, L. S. (2023). Green tea consumption and the risk of coronary heart disease: A systematic review and meta-analysis of cohort studies. Nutrition, Metabolism, and Cardiovascular Diseases : NMCD, 33(4), 715–723. https://doi.org/10.1016/j.numecd.2023.01.017
  • Wang, X., Liu, F., Li, J., Yang, X., Chen, J., Cao, J., Wu, X., Lu, X., Huang, J., Li, Y., Zhao, L., Shen, C., Hu, D., Yu, L., Liu, X., Wu, X., Wu, S., & Gu, D. (2020). Tea consumption and the risk of atherosclerotic cardiovascular disease and all-cause mortality: The China-PAR project. European Journal of Preventive Cardiology, 27(18), 1956–1963. https://doi.org/10.1177/2047487319894685
  • Weylandt, K. H., Serini, S., Chen, Y. Q., Su, H. M., Lim, K., Cittadini, A., & Calviello, G. (2015). Omega-3 polyunsaturated fatty acids: the way forward in times of mixed evidence. BioMed Research International, 2015, 143109. https://doi.org/10.1155/2015/143109
  • Xu, C., Mathews, A. E., Rodrigues, C., Eudy, B. J., Rowe, C. A., O'Donoughue, A., & Percival, S. S. (2018). Aged garlic extract supplementation modifies inflammation and immunity of adults with obesity: A randomized, double-blind, placebo-controlled clinical trial. Clinical Nutrition ESPEN, 24, 148–155. https://doi.org/10.1016/j.clnesp.2017.11.010
  • Xu, R., Yang, K., Ding, J., & Chen, G. (2020). Effect of green tea supplementation on blood pressure: A systematic review and meta-analysis of randomized controlled trials. Medicine, 99(6), e19047. https://doi.org/10.1097/MD.0000000000019047
  • Yang, J., Zhou, J., Yang, J., Lou, H., Zhao, B., Chi, J., & Guo, H. (2023). Dark chocolate ıntake and cardiovascular diseases: a mendelian randomization study. Research Squary, (1). https://doi.org/10.21203/rs.3.rs-2919868/v1 Yi, S. Y., Steffen, L. M., Zhou, X., Shikany, J. M., & Jacobs, D. R., Jr (2022). Association of nut consumption with CVD risk factors in young to middle-aged adults: The Coronary Artery Risk Development in Young Adults (CARDIA) study. Nutrition, metabolism and cardiovascular disease: NMCD, 32(10), 2321-2329. https://doi.org/10.1016/j.numecd.2022.07.013
  • Yilmaz, M. I., Romano, M., Basarali, M. K., Elzagallaai, A., Karaman, M., Demir, Z., Demir, M. F., Akcay, F., Seyrek, M., Haksever, N., Piskin, D., Cimaz, R., Rieder, M. J., & Demirkaya, E. (2020). The Effect of Corrected Inflammation, Oxidative Stress and Endothelial Dysfunction on Fmd Levels in Patients with Selected Chronic Diseases: A Quasi-Experimental Study. Scientific reports, 10(1), 9018. https://doi.org/10.1038/s41598-020-65528-6
There are 82 citations in total.

Details

Primary Language Turkish
Subjects Nutritional Science, Clinical Nutrition
Journal Section Review
Authors

Bahar Yalçın 0000-0003-4036-7096

Melike Nur Özen 0009-0004-2330-8152

Early Pub Date April 29, 2024
Publication Date April 30, 2024
Submission Date December 1, 2023
Acceptance Date March 27, 2024
Published in Issue Year 2024

Cite

APA Yalçın, B., & Özen, M. N. (2024). Kardiyovasküler Hastalıklar ve Fonksiyonel Besinler. Cumhuriyet Üniversitesi Sağlık Bilimleri Enstitüsü Dergisi, 9(1), 87-97. https://doi.org/10.51754/cusbed.1398809

   ici2.png    logo.png        asos-index.png       crossref-logo-landscape-200.png     logo.png       search-result-logo-horizontal-TEST.jpg 

     

logo.png    scilit.jpg     goole_scholar.jpg       logo.png    logo.png


f9ab67f.png                    download