Allojenik Kök Hücre Nakliyle İlişkili BK Virüs-Hemorajik Sistit

Hicran Yıldız; Yasemin Karacan

doi:10.51754/cusbed.812060

Review

Allojenik Kök Hücre Nakliyle İlişkili BK Virüs-Hemorajik Sistit

Year 2021, Volume: 6 Issue: 2, 103 - 111, 30.08.2021

Hicran Yıldız , Yasemin Karacan

https://doi.org/10.51754/cusbed.812060

Abstract

Allojenik kök hücre nakli (AKHN) yapılan hastalarda BK virüsü hemorajik sistiti (BKV-HS), potansiyel bir morbidite ve mortalite nedenidir. BKV reaktivasyonu, asemptomatik viral enfeksiyondan hemorajik sistit veya nefrite kadar değişen farklı sorunlara neden olabilir. Ayrıca, uzun süre hastanede kalışa neden olabilir. Özellikle, hematopoietik kök hücre nakli alıcılarında egrafman sonrası gelişen akut hemorajik sistitin BK virüsü ile ilişkili olabileceği düşünülmektedir. Bu derlemede, AKHN uygulanan hastalarda görülebilecek BKV-HS’ in önemine dikkat çekilmekte, hemşirelerin bu hasta grubunda BKV ile ilişkili hemorajik sistiti önleme ve yönetmedeki rolüne değinilmektedir.

Keywords

hemorajik sistit, BK Virüs, allojenik kök hücre nakli

References

1. Ando M (2018) An Overview of Kidney Disease Following Hematopoietic Cell Transplantation. Intern Med. 57(11):1503–8.
2. Araujo DD, Rodrigues AB, de Oliveira PP, Silva LS, Vecchia BP, da Silveira EAA. Nursing diagnoses and interventions for patients with graft-versus-host disease submitted to hematopoietic stem cell transplantation . Cogitare Enferm. 2015;20(2):305-313.
1. Ballen KK, Gluckman E, Broxmeyer HE (2014) Review Article Umbilical cord blood transplantation : the fi rst 25 years and beyond. Blood. 122(4):491–9.
2. Beksaç M (2020) Kök Hücre. https://services.tubitak.gov.tr/edergi/user/yaziForm1.pdf (accessed June 2020.
3. Bogdanovic G, Priftakis P, Giraud G, Kuzniar M, Ferraldeschi R, Kokhaei P, et al. (2004) Association between a high BK virus load in urine samples of patients with graft-versus-host disease and development of hemorrhagic cystitis after hematopoietic stem cell transplantation. J Clin Microbiol. 42(11):5394–6.
4. Cesaro S, Dalianis T, Rinaldo CH, Koskenvuo M, Pegoraro A, Einsele H, Cordonnier C, Hirsch HH (2018) Members of the ECIL-6. ECIL Guidelines for the prevention, diagnosis and treatment of BK polyomavirusassociated haemorrhagic cystitis in haematopoietic stem cell transplant recipients. J Antimicrob Chemother. 2018;73(1):12-21. https://doi.org/10.1093/jac/dkx324
5. Childs R, Sanchez C, Engler H, Preuss J, Rosenfeld S, Dunbar C, et al. (1998) High incidence of adeno- and polyomavirus-induced hemorrhagic cystitis in bone marrow allotransplantation for hematological malignancy following T cell depletion and cyclosporine. Bone Marrow Transplant. 1998;22(9):889–93.
6. Dalianis T, Eriksson BM, Felldin M, Friman V, Hammarin AL, Herthelius M, et al. (2019) Management of BK-virus infection–Swedish recommendations. Infect Dis (Auckl) [Internet].51(7):479–84. (doi:/10.1080/23744235.2019.1595130)
7. Dimitrova N, Zamudio JR, Jong RM, Soukup D, Resnick R, Sarma K, et al. (2017) Public Access NIH Public Access. PLoS One. 32(7):736–40.
8. Europe Bone Marrow Transplantation (2019) The EBMT Handbook Hematopoietic Stem Cell Transplantation and Cellular Therapies [Internet]. 2019. 1–688 p. Available from: 10.1007/978-3-030-02278-5
9. Gemalmaz H (2007) Hemorajik Sistit. Turkiye Klin J Surg Med Sci [Internet]. 2007;3(20):41–7. Available from: http://www.turkiyeklinikleri.com/article/en-hemorajik-sistit-49719.html
10. Harkensee C, Vasdev N, Gennery AR, Willets IE, Taylor C (2008) Prevention and management of BK‐virus associated haemorrhagic cystitis in children following haematopoietic stem cell transplantation – a systematic review and evidence‐based guidance for clinical management. British Journal of Haematology, 142, 717–731, 2008.
11. Henig I, Zuckerman T (2014) Hematopoietic Stem Cell Transplantation—50 Years of Evolution and Future Perspectives. Rambam Maimonides Med J. 2014;5(4):e0028.
12. Imlay H, Xie H, Leisenring WM, Duke ER, Kimball LE, Huang M, Pergam SA, Hill JA, Jerome KR, Milano F, Nichols GW, Pang PS, Hirsh HH, Limaye AP, Boeckh M (2020) Presentation of BK polyomavirus–associated hemorrhagic cystitis after allogeneic hematopoietic cell transplantation. Blood Adv . 4 (4): 617–628.
13. Krishnappa V, Gupta M, Manu G, Kwatra S, Owusu OT, Raina R (2016) Acute Kidney Injury in Hematopoietic Stem Cell Transplantation: A review. Int J Nephrol.
14. Kontoyiannis DP (2016) Infections following allogeneic stem cell transplantation: New concepts, improved insights, and renewed hope for better outcomes. Virulence [Internet].7(8):898–900. (doi:10.1080/21505594.2016.1252019)
15. Lean K, Nawaz RF, Jawad S, Vincent C (2019) Reducing urinary tract infections in care homes by improving hydration. BMJ Open Qual [Internet]. 8(3):e000563. (doi:10.1136/bmjoq-2018-000563)
16. Lee HS, Le J (2018) Urinary Tract Infections. PSAP 2018 B 1, Infect Dis. 2018; (Sobel 2014):7–28.
17. Lee S, Ahn J, Jung S , Ahn S , Kim J, Jang H, Kang S, Jang M, Yang D, Kim Y, Lee J, Kim H (2015) Treatment of BK virus-associated hemorrhagic cystitis with low-dose intravenous cidofovir in patients undergoing allogeneic hematopoietic cell transplantation Korean J Intern Med. 30:212-218 http://dx.doi.org/10.3904/kjim.2015.30.2.212
18. Manikandan R, Kumar S, Dorairajan LN (2010) Hemorrhagic cystitis: A challenge to the urologist. Indian J Urol. 26(2):159–66.
19. Nar I (2014) Hematopoeti̇k kök hücre transplantasyonu yapilmiş çocuk ve adolesanlarda uzun dönem endokri̇noloji̇k kompli̇kasyonlar. Hacettepe Üniversitesi Tıp Fakültesi Çocuk Sağlığı ve Hast AD, Uzm tezi;Ankara.
20. Rorije NMG, Shea MM, Satyanarayana G, Hammond SP, Ho VT, Baden LR, et al. BK virus disease after allogeneic stem cell transplantation: A cohort analysis. Biol Blood Marrow Transplant [Internet]. 2014;20(4):564–70.
21. Silva L de P, Patah PA, Saliba RM, Szewczyk NA, Gilman L, Neumann J et all. (2010). Hemorrhagic cystitis after allogeneic hematopoietic stem cell transplants is the complex result of BK virus infection, preparative regimen intensity and donor type. Haematologica. 2010;95(7):1183–90.
22. Schneidewind L, Neumann T, Kranz J, Knoll F, Pelzer AE, Schmidt C, et al. (2017) Nationwide survey of BK polyomavirus associated hemorrhagic cystitis in adult allogeneic stem cell transplantation among haematologists and urologists. Ann Hematol. 2017;96(5):797–803.
23. Seber A, Shu XO, Defor T, Sencer S, Ramsay N (1999) Risk factors for severe hemorrhagic cystitis following BMT. Bone Marrow Transplant. 23(1):35–40.
24. Sloan M, Cancer K. Adverse Late and Long- Term Treatment Effects in Adult Allogeneic Hematopoietic Stem Cell Transplant Survivors. 2015;115(11).
25. Soysal T (2004) Hemorajik Sistit. Türk Hematol Derneği Kan ve Kem İliğiTransplantasyonu Kursu [Internet].192–4. Available from: http://www.turkiyeklinikleri.com/article/en-hemorajik-sistit-49719.html
26. Tanaka T, Nakashima Y, Sasaki H, Masaki M, Mogi A, Tamura K, et al. (2019) Severe Hemorrhagic Cystitis Caused by Cyclophosphamide and Capecitabine Therapy in Breast Cancer Patients: Two Case Reports and Literature Review. Case Rep Oncol. 12(1):69–75.
27. Trajkovska I, Hasan T, Nedeska-Minova N, Georgievski B, Cevreska L, Gacovski A (2017) Early and late complications in patients with allogeneic transplantation of hematopoietic stem cell – Case report. Maced J Med Sci. 2017;5(3):340–3.
28. Tichelli A, Rovó A, Gratwohl A (2008)Late pulmonary, cardiovascular, and renal complications after hematopoietic stem cell transplantation and recommended screening practices. Hematology Am Soc Hematol Educ Program. 2008;125–33.
29. Ünal A, Sarı I (2004) Kök Hücre Kaynağı ve Seçimi. Türk Hematol Derneği, Kan ve Kemik İliği Transplantasyonu Kursu. 2004;37–41. 30. Visintini C, Venturini M, Botti S , Gargiulo G, Palese A (2019) Nursing Management of Haemorrhagic Cystitis in Patients Undergoing Haematopoietic Stem Cell Transplantation: a Multicentre Italian Survey. Mediterr J Hematol Infect Dis 2019; 11, 1-10.
31. Yakushijin K, Atsuta Y, Doki N, Yokota A, Kanamori H, Miyamoto T, et al. (2016) Sinusoidal obstruction syndrome after allogeneic hematopoietic stem cell transplantation: Incidence, risk factors and outcomes. Bone Marrow Transplant [Internet]. 51(3):403–9. (doi:10.1038/bmt.2015.283
32. Zulu S, Kenyon M (2018) The European Blood and Marrow Transplantation Textbook for Nurses. Eur Blood Marrow Transplant Textb Nurses.

BK Virus-Hemorrhagıc Cystitis Related To Allogeneic Stem Cell Transplantation

Year 2021, Volume: 6 Issue: 2, 103 - 111, 30.08.2021

Hicran Yıldız , Yasemin Karacan

https://doi.org/10.51754/cusbed.812060

Abstract

BK virus-hemorrhagic cystitis (BKV-HC) is a potential cause of mortality and morbidity in patients having after allogeneic stem cell transplantation (ASCT). BKV reactivation may cause different problems ranging from asymptomatic viral infection to hemorrhagic cystitis or nephritis. It can also cause to stay a long term hospital. Especially HC following engraftment in hematopoietic stem cell transplant recipients could be associated with BK virus. In this review, attention is drawn to the importance of BKV-HC, which can be seen in patients undergoing ASCT, and the role of nurses in preventing and managing BKV-related hemorrhagic cystitis in this patient group.

Keywords

Hemorrhagic cystitis, BK virüs, allogeneic stem cell transplantation.

References

1. Ando M (2018) An Overview of Kidney Disease Following Hematopoietic Cell Transplantation. Intern Med. 57(11):1503–8.
2. Araujo DD, Rodrigues AB, de Oliveira PP, Silva LS, Vecchia BP, da Silveira EAA. Nursing diagnoses and interventions for patients with graft-versus-host disease submitted to hematopoietic stem cell transplantation . Cogitare Enferm. 2015;20(2):305-313.
1. Ballen KK, Gluckman E, Broxmeyer HE (2014) Review Article Umbilical cord blood transplantation : the fi rst 25 years and beyond. Blood. 122(4):491–9.
2. Beksaç M (2020) Kök Hücre. https://services.tubitak.gov.tr/edergi/user/yaziForm1.pdf (accessed June 2020.
3. Bogdanovic G, Priftakis P, Giraud G, Kuzniar M, Ferraldeschi R, Kokhaei P, et al. (2004) Association between a high BK virus load in urine samples of patients with graft-versus-host disease and development of hemorrhagic cystitis after hematopoietic stem cell transplantation. J Clin Microbiol. 42(11):5394–6.
4. Cesaro S, Dalianis T, Rinaldo CH, Koskenvuo M, Pegoraro A, Einsele H, Cordonnier C, Hirsch HH (2018) Members of the ECIL-6. ECIL Guidelines for the prevention, diagnosis and treatment of BK polyomavirusassociated haemorrhagic cystitis in haematopoietic stem cell transplant recipients. J Antimicrob Chemother. 2018;73(1):12-21. https://doi.org/10.1093/jac/dkx324
5. Childs R, Sanchez C, Engler H, Preuss J, Rosenfeld S, Dunbar C, et al. (1998) High incidence of adeno- and polyomavirus-induced hemorrhagic cystitis in bone marrow allotransplantation for hematological malignancy following T cell depletion and cyclosporine. Bone Marrow Transplant. 1998;22(9):889–93.
6. Dalianis T, Eriksson BM, Felldin M, Friman V, Hammarin AL, Herthelius M, et al. (2019) Management of BK-virus infection–Swedish recommendations. Infect Dis (Auckl) [Internet].51(7):479–84. (doi:/10.1080/23744235.2019.1595130)
7. Dimitrova N, Zamudio JR, Jong RM, Soukup D, Resnick R, Sarma K, et al. (2017) Public Access NIH Public Access. PLoS One. 32(7):736–40.
8. Europe Bone Marrow Transplantation (2019) The EBMT Handbook Hematopoietic Stem Cell Transplantation and Cellular Therapies [Internet]. 2019. 1–688 p. Available from: 10.1007/978-3-030-02278-5
9. Gemalmaz H (2007) Hemorajik Sistit. Turkiye Klin J Surg Med Sci [Internet]. 2007;3(20):41–7. Available from: http://www.turkiyeklinikleri.com/article/en-hemorajik-sistit-49719.html
10. Harkensee C, Vasdev N, Gennery AR, Willets IE, Taylor C (2008) Prevention and management of BK‐virus associated haemorrhagic cystitis in children following haematopoietic stem cell transplantation – a systematic review and evidence‐based guidance for clinical management. British Journal of Haematology, 142, 717–731, 2008.
11. Henig I, Zuckerman T (2014) Hematopoietic Stem Cell Transplantation—50 Years of Evolution and Future Perspectives. Rambam Maimonides Med J. 2014;5(4):e0028.
12. Imlay H, Xie H, Leisenring WM, Duke ER, Kimball LE, Huang M, Pergam SA, Hill JA, Jerome KR, Milano F, Nichols GW, Pang PS, Hirsh HH, Limaye AP, Boeckh M (2020) Presentation of BK polyomavirus–associated hemorrhagic cystitis after allogeneic hematopoietic cell transplantation. Blood Adv . 4 (4): 617–628.
13. Krishnappa V, Gupta M, Manu G, Kwatra S, Owusu OT, Raina R (2016) Acute Kidney Injury in Hematopoietic Stem Cell Transplantation: A review. Int J Nephrol.
14. Kontoyiannis DP (2016) Infections following allogeneic stem cell transplantation: New concepts, improved insights, and renewed hope for better outcomes. Virulence [Internet].7(8):898–900. (doi:10.1080/21505594.2016.1252019)
15. Lean K, Nawaz RF, Jawad S, Vincent C (2019) Reducing urinary tract infections in care homes by improving hydration. BMJ Open Qual [Internet]. 8(3):e000563. (doi:10.1136/bmjoq-2018-000563)
16. Lee HS, Le J (2018) Urinary Tract Infections. PSAP 2018 B 1, Infect Dis. 2018; (Sobel 2014):7–28.
17. Lee S, Ahn J, Jung S , Ahn S , Kim J, Jang H, Kang S, Jang M, Yang D, Kim Y, Lee J, Kim H (2015) Treatment of BK virus-associated hemorrhagic cystitis with low-dose intravenous cidofovir in patients undergoing allogeneic hematopoietic cell transplantation Korean J Intern Med. 30:212-218 http://dx.doi.org/10.3904/kjim.2015.30.2.212
18. Manikandan R, Kumar S, Dorairajan LN (2010) Hemorrhagic cystitis: A challenge to the urologist. Indian J Urol. 26(2):159–66.
19. Nar I (2014) Hematopoeti̇k kök hücre transplantasyonu yapilmiş çocuk ve adolesanlarda uzun dönem endokri̇noloji̇k kompli̇kasyonlar. Hacettepe Üniversitesi Tıp Fakültesi Çocuk Sağlığı ve Hast AD, Uzm tezi;Ankara.
20. Rorije NMG, Shea MM, Satyanarayana G, Hammond SP, Ho VT, Baden LR, et al. BK virus disease after allogeneic stem cell transplantation: A cohort analysis. Biol Blood Marrow Transplant [Internet]. 2014;20(4):564–70.
21. Silva L de P, Patah PA, Saliba RM, Szewczyk NA, Gilman L, Neumann J et all. (2010). Hemorrhagic cystitis after allogeneic hematopoietic stem cell transplants is the complex result of BK virus infection, preparative regimen intensity and donor type. Haematologica. 2010;95(7):1183–90.
22. Schneidewind L, Neumann T, Kranz J, Knoll F, Pelzer AE, Schmidt C, et al. (2017) Nationwide survey of BK polyomavirus associated hemorrhagic cystitis in adult allogeneic stem cell transplantation among haematologists and urologists. Ann Hematol. 2017;96(5):797–803.
23. Seber A, Shu XO, Defor T, Sencer S, Ramsay N (1999) Risk factors for severe hemorrhagic cystitis following BMT. Bone Marrow Transplant. 23(1):35–40.
24. Sloan M, Cancer K. Adverse Late and Long- Term Treatment Effects in Adult Allogeneic Hematopoietic Stem Cell Transplant Survivors. 2015;115(11).
25. Soysal T (2004) Hemorajik Sistit. Türk Hematol Derneği Kan ve Kem İliğiTransplantasyonu Kursu [Internet].192–4. Available from: http://www.turkiyeklinikleri.com/article/en-hemorajik-sistit-49719.html
26. Tanaka T, Nakashima Y, Sasaki H, Masaki M, Mogi A, Tamura K, et al. (2019) Severe Hemorrhagic Cystitis Caused by Cyclophosphamide and Capecitabine Therapy in Breast Cancer Patients: Two Case Reports and Literature Review. Case Rep Oncol. 12(1):69–75.
27. Trajkovska I, Hasan T, Nedeska-Minova N, Georgievski B, Cevreska L, Gacovski A (2017) Early and late complications in patients with allogeneic transplantation of hematopoietic stem cell – Case report. Maced J Med Sci. 2017;5(3):340–3.
28. Tichelli A, Rovó A, Gratwohl A (2008)Late pulmonary, cardiovascular, and renal complications after hematopoietic stem cell transplantation and recommended screening practices. Hematology Am Soc Hematol Educ Program. 2008;125–33.
29. Ünal A, Sarı I (2004) Kök Hücre Kaynağı ve Seçimi. Türk Hematol Derneği, Kan ve Kemik İliği Transplantasyonu Kursu. 2004;37–41. 30. Visintini C, Venturini M, Botti S , Gargiulo G, Palese A (2019) Nursing Management of Haemorrhagic Cystitis in Patients Undergoing Haematopoietic Stem Cell Transplantation: a Multicentre Italian Survey. Mediterr J Hematol Infect Dis 2019; 11, 1-10.
31. Yakushijin K, Atsuta Y, Doki N, Yokota A, Kanamori H, Miyamoto T, et al. (2016) Sinusoidal obstruction syndrome after allogeneic hematopoietic stem cell transplantation: Incidence, risk factors and outcomes. Bone Marrow Transplant [Internet]. 51(3):403–9. (doi:10.1038/bmt.2015.283
32. Zulu S, Kenyon M (2018) The European Blood and Marrow Transplantation Textbook for Nurses. Eur Blood Marrow Transplant Textb Nurses.

There are 33 citations in total.

Details

Primary Language	Turkish
Subjects	Health Care Administration
Journal Section	Review
Authors	Hicran Yıldız 0000-0003-4241-5231 Yasemin Karacan 0000-0001-8616-4935
Publication Date	August 30, 2021
Published in Issue	Year 2021Volume: 6 Issue: 2

Cite

APA	Yıldız, H., & Karacan, Y. (2021). Allojenik Kök Hücre Nakliyle İlişkili BK Virüs-Hemorajik Sistit. Cumhuriyet Üniversitesi Sağlık Bilimleri Enstitüsü Dergisi, 6(2), 103-111. https://doi.org/10.51754/cusbed.812060

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