Review
Year 2020,
Volume: 5 Issue: 2, 73 - 82, 10.09.2020
Abstract
Kefir, a fermented beverage, has probiotic property. It contains many macro and micro nutrients. Traditional kefir production is done with kefir grains and cow's milk. Kefir and its microorganisms have been reported to have many beneficial health effects. Today, kefir is being used for alternative treatment of cancer, an important disease. In order to better understand the anticarcinogenic effects of kefir, large-scale controlled human studies are needed. In this review, the effects of kefir on cancer are discussed by reviewing the literature.
Keywords
References
- Referans1. Türk Gıda Kodeksi Fermente Süt Ürünleri Tebliği Taslağı, Tebliğ No:Taslak/2017.
- Referans2. Alptekin D, Uyar S. (1997). Değişik İnkübasyon Sıcaklılarının Kefir ve Kefir Danelerinin Kimi Özelliklerine Etkisi Üzerinde Bir Araştırma (Tez). Ege Üniversitesi Ziraat Fakültesi Süt Teknolojisi Bölümü.
- Referans3. Ötleş S, Çağındı Ö. (2003). Kefir: A Probiotic Dairy Composition, Nutritional and Therapeutic Aspects. Pakistan Journal of Nutrition; 2(2): 54-59.
- Referans4. Yılmaz L, Yılsay TO, Bayazıt AA. (2006). The sensory characteristics of berry flavoured kefir. J. Food Sci; 24: 26-3.
- Referans5. Ender G, Karagözlü C, Yerlikaya O, Akbulut N. (2006). Dünyada ve Türkiye'de tüketimi artan fermente süt içecekleri. Türkiye 9. Gıda Kongresi; 24-26 Mayıs 2006, Bolu s: 149-152.
- Referans6. Prado MR, Blandon LM,Vandenberge PS, Rodrigues C, Castro GR, Soccol CR. et al. (2015). Milk kefir: composition, microbial cultures, biological activities, and related products. Frontiers in microbiology; 6, (1177).
- Referans7. Tomar O, Çağlar A, Akarca G. (2017). Kefir ve sağlık açısından önemi. AKU J. Sci; 027202:834-853.
- Referans8. Altınkılıç. (2013). Kefir nedir. http://www.altinkilic.com/ kefir_nedir.html. Erişim tarihi:21/04/2017.
- Referans9. Nielsen B, Gürakan GC, Ünlü G. (2014). Kefir: A Multifaceted Fermented Dairy Product. Probiotics & Antimicro. Prot; 6:123–13.
- Referans10. Sharifi M, Moridnia A, Mortazavi D, Salehi M, Bagheri M, Sheikhi A. (2017). Kefir: a powerful probiotics with anticancer properties. Med Onkol; 34(11):183.
- Referans11. Khoury N, El-Hayek S, Tarras O, El-Sabban M, El-Sibai M, Rizk S. (2014). Kefr exhibits anti-proliferative and pro-apoptotic efects on colon adenocarcinoma cells with no signifcant efects on cell migration and invasion. Int J Oncol;45(5):2117–27.
- Referans12. Gao J, Gu F, Ruan H, Chen Q, He J, He G. (2013). Induction of apoptosis of gastric cancer cells SGC7901 in vitro by a cell-free fraction of Tibetan kefir. Int. Dairy J; 30:14–18.
- Referans13. Grishina A, Kulikova I, Alieva L, Dodson A, Rowland I, Jin J. (2011). Antigenotoxic effect of kefir and ayran supernatants on fecal water-induced DNA damage in human colon cells. Nutr. Cancer; 63:73–79.
- Referans14. Rizk S, Maalouf K, Baydoun E. (2009). The antiproliferative effect of kefir cell-free fraction on HuT-102 malignant T lymphocytes. Clin. Lymphoma. Myeloma; 9:198–203.
- Referans15. Maalouf K, Baydoun E, Rizk S. (2011). Kefir induces cell-cycle arrest and apoptosis in HTLV-1-negative malignant T-lymphocytes. Cancer Manag. Res; 3:39–47.
- Referans16. Chen C, Chan HM, Kubaw S. (2006). Kefir extracts suppress in vitro proliferation of estrogen-dependent human breast cancer cells but not normal mammary epithelial cells. J Med Food; 10 (3): 416–422.
- Referans17. Nagira T, Narisawa J, Teruya K, Katakura Y, Shim SY, Kusumoto K et al. (2002). Suppression of UVC-induced cell damage and enhancement of DNA repair by the fermented milk, kefir. Cytotechnology; 40:125–137.
- Referans18. de Moreno de LeBlanc A, Matar C, Farnworth E, Perdigon G. (2006). Study of cytokines involved in the prevention of a murine experimental breast cancer by kefir. Cytokine; 34:1–8.
- Referans19. Çevikbaş A, Yemni E, Ezzedenn FW, Yardmcı T, Çevikbas U, Stohs SJ. (1994). Antitumoural, antibacterial and antifungal activities of kefir and kefir grain. Phytotherapy Research; 8: 78-82.
- Referans20. Furukawa N, Matsuoka A, Yamanaka Y. (1990). Effects of orally administered yogurt and kefir on tumor growth in mice. Journal of Japanese Society of Nutrition and Food Science; 43(6): 450-453.
- Referans21. Murofushi M, Shiomi M, Aibara K. (1983). Effect of orally administered polysaccharide from kefir grain on delayed type hypersensitivity and tumor growht in mice. Japanese Journal of Medical Science and Biology; 36(19): 49-53.
- Referans22. Shiomi M, Sasaki K, Murofushi M, Aibara K. (1982). Antitumor activity in mice of orally administered polysaccharide from kefir grain. Japanese Journal of Medical Science and Biology; 35(2): 75-80.
Year 2020,
Volume: 5 Issue: 2, 73 - 82, 10.09.2020
Abstract
Fermente bir içecek olan kefir probiyotik özelliğe sahiptir. İçeriğinde birçok makro ve mikro besin ögesi bulunmaktadır. Geleneksel kefir üretimi kefir daneleri ve inek sütü ile yapılmaktadır. Kefir ve içerdiği mikroorganizmaların sağlığa yararlı birçok etkisi bildirilmiştir. Günümüzde önemli bir hastalık olan kanserin alternatif tedavisi için kefir kullanılmaktadır. Kefirin antikarsinojenik etkilerinin daha iyi anlaşılabilmesi için geniş çaplı kontrollü insan çalışmaların yapılmasına gereksinim duyulmaktadır. Bu derleme yazıda kefirin kanser üzerine etkileri literatürdeki yayınlar değerlendirilerek irdelenmiştir.
Keywords
References
- Referans1. Türk Gıda Kodeksi Fermente Süt Ürünleri Tebliği Taslağı, Tebliğ No:Taslak/2017.
- Referans2. Alptekin D, Uyar S. (1997). Değişik İnkübasyon Sıcaklılarının Kefir ve Kefir Danelerinin Kimi Özelliklerine Etkisi Üzerinde Bir Araştırma (Tez). Ege Üniversitesi Ziraat Fakültesi Süt Teknolojisi Bölümü.
- Referans3. Ötleş S, Çağındı Ö. (2003). Kefir: A Probiotic Dairy Composition, Nutritional and Therapeutic Aspects. Pakistan Journal of Nutrition; 2(2): 54-59.
- Referans4. Yılmaz L, Yılsay TO, Bayazıt AA. (2006). The sensory characteristics of berry flavoured kefir. J. Food Sci; 24: 26-3.
- Referans5. Ender G, Karagözlü C, Yerlikaya O, Akbulut N. (2006). Dünyada ve Türkiye'de tüketimi artan fermente süt içecekleri. Türkiye 9. Gıda Kongresi; 24-26 Mayıs 2006, Bolu s: 149-152.
- Referans6. Prado MR, Blandon LM,Vandenberge PS, Rodrigues C, Castro GR, Soccol CR. et al. (2015). Milk kefir: composition, microbial cultures, biological activities, and related products. Frontiers in microbiology; 6, (1177).
- Referans7. Tomar O, Çağlar A, Akarca G. (2017). Kefir ve sağlık açısından önemi. AKU J. Sci; 027202:834-853.
- Referans8. Altınkılıç. (2013). Kefir nedir. http://www.altinkilic.com/ kefir_nedir.html. Erişim tarihi:21/04/2017.
- Referans9. Nielsen B, Gürakan GC, Ünlü G. (2014). Kefir: A Multifaceted Fermented Dairy Product. Probiotics & Antimicro. Prot; 6:123–13.
- Referans10. Sharifi M, Moridnia A, Mortazavi D, Salehi M, Bagheri M, Sheikhi A. (2017). Kefir: a powerful probiotics with anticancer properties. Med Onkol; 34(11):183.
- Referans11. Khoury N, El-Hayek S, Tarras O, El-Sabban M, El-Sibai M, Rizk S. (2014). Kefr exhibits anti-proliferative and pro-apoptotic efects on colon adenocarcinoma cells with no signifcant efects on cell migration and invasion. Int J Oncol;45(5):2117–27.
- Referans12. Gao J, Gu F, Ruan H, Chen Q, He J, He G. (2013). Induction of apoptosis of gastric cancer cells SGC7901 in vitro by a cell-free fraction of Tibetan kefir. Int. Dairy J; 30:14–18.
- Referans13. Grishina A, Kulikova I, Alieva L, Dodson A, Rowland I, Jin J. (2011). Antigenotoxic effect of kefir and ayran supernatants on fecal water-induced DNA damage in human colon cells. Nutr. Cancer; 63:73–79.
- Referans14. Rizk S, Maalouf K, Baydoun E. (2009). The antiproliferative effect of kefir cell-free fraction on HuT-102 malignant T lymphocytes. Clin. Lymphoma. Myeloma; 9:198–203.
- Referans15. Maalouf K, Baydoun E, Rizk S. (2011). Kefir induces cell-cycle arrest and apoptosis in HTLV-1-negative malignant T-lymphocytes. Cancer Manag. Res; 3:39–47.
- Referans16. Chen C, Chan HM, Kubaw S. (2006). Kefir extracts suppress in vitro proliferation of estrogen-dependent human breast cancer cells but not normal mammary epithelial cells. J Med Food; 10 (3): 416–422.
- Referans17. Nagira T, Narisawa J, Teruya K, Katakura Y, Shim SY, Kusumoto K et al. (2002). Suppression of UVC-induced cell damage and enhancement of DNA repair by the fermented milk, kefir. Cytotechnology; 40:125–137.
- Referans18. de Moreno de LeBlanc A, Matar C, Farnworth E, Perdigon G. (2006). Study of cytokines involved in the prevention of a murine experimental breast cancer by kefir. Cytokine; 34:1–8.
- Referans19. Çevikbaş A, Yemni E, Ezzedenn FW, Yardmcı T, Çevikbas U, Stohs SJ. (1994). Antitumoural, antibacterial and antifungal activities of kefir and kefir grain. Phytotherapy Research; 8: 78-82.
- Referans20. Furukawa N, Matsuoka A, Yamanaka Y. (1990). Effects of orally administered yogurt and kefir on tumor growth in mice. Journal of Japanese Society of Nutrition and Food Science; 43(6): 450-453.
- Referans21. Murofushi M, Shiomi M, Aibara K. (1983). Effect of orally administered polysaccharide from kefir grain on delayed type hypersensitivity and tumor growht in mice. Japanese Journal of Medical Science and Biology; 36(19): 49-53.
- Referans22. Shiomi M, Sasaki K, Murofushi M, Aibara K. (1982). Antitumor activity in mice of orally administered polysaccharide from kefir grain. Japanese Journal of Medical Science and Biology; 35(2): 75-80.
There are 22 citations in total.
Details
| Primary Language | Turkish |
|---|---|
| Subjects | Health Care Administration |
| Journal Section | Review |
| Authors | |
| Publication Date | September 10, 2020 |
| Published in Issue | Year 2020Volume: 5 Issue: 2 |
