Gebelikte kardiyovasküler hastalıklar dolaylı anne ölümlerinin başlıca nedenidir. İlerleyen gebelik yaşı, obezite, sedanter yaşam tarzı ve değişen beslenme alışkanlıkları gibi faktörler kardiyovasküler sistem hastalıklarına bağlı anne ölüm oranlarında artmaya sebep olmaktadır. Gebelik sırasında ayrıntılı öykü alma ve fizik muayene ile kardiyovasküler risk değerlendirmesi yapılmalıdır. Bu doğrultuda gebenin kalp hastalıkları sınıflandırma sistemine göre derecesi ve saptanan kalp rahatsızlıkları doğrultusunda gebeliği ve doğumu planlanmalıdır. Kalp hastası kadınların mutlaka hastane ortamında doğum yapması sağlanmalıdır. Deneyimli bir sağlık ekibi tarafından doğum şekli ve doğum yerine karar verilmelidir. Doğum multidisipliner yaklaşım uygulanabilecek bir merkezde yapılmalıdır. Bireysel doğum planıyla birlikte genellikle vajinal doğum tercih edilebilir. Kadının kullandığı aldığı ilaçlar, doğum sonu ve laktasyon sürecinde de güvenlik açısından değerlendirilmelidir. Bu derlemenin amacı gebelik, doğum ve doğum sonu dönemde kardiyovasküler hastalıkları literatür doğrultusunda irdelemektir.
Derleme yazısı olması nedeniyle etik kurul izni bulunmamaktadır.
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Thanks
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References
ACOG Practice Bulletin No. 212 (2019): Pregnancy and heart disease. Obstetrics & Gynecology, 133(5), e320-e356. https://doi.org/10.1097/AOG.0000000000003243
Balci, A., Sollie-Szarynska, K. M., van der Bijl, A. G., Ruys, T. P., Mulder, B. J., Roos-Hesselink, J. W., ... & Pieper, P. G. (2014). Prospective validation and assessment of cardiovascular and offspring risk models for pregnant women with congenital heart disease. Heart, 100(17), 1373-1381. https://doi.org/10.1136/heartjnl-2014-305597
Beaton, A., Okello, E., Scheel, A., DeWyer, A., Ssembatya, R., Baaka, O., ... & Sable, C. (2019). Impact of heart disease on maternal, fetal and neonatal outcomes in a low-resource setting. Heart, 105(10), 755-760. https://doi.org/10.1136/heartjnl-2018-313810
Bennett, J. A., Riegel, B., Bittner, V., & Nichols, J. (2002). Validity and reliability of the NYHA classes for measuring research outcomes in patients with cardiac disease. Heart & Lung, 31(4), 262-270. https://doi.org/10.1067/mhl.2002.124554
Bredy, C., Deville, F., Huguet, H., Picot, M. C., De La Villeon, G., Abassi, H., ... & Amedro, P. (2023). Which risk score best predicts cardiovascular outcome in pregnant women with congenital heart disease?. European Heart Journal-Quality of Care and Clinical Outcomes, 9(2), 177-183. https://doi.org/10.1093/ehjqcco/qcac019
Bright, R. A., Lima, F. V., Avila, C., Butler, J., & Stergiopoulos, K. (2021). Maternal Heart Failure. Journal of the American Heart Association, 10(14), e021019. https://doi.org/10.1161/JAHA.121.021019
Canobbio, M. M., Warnes, C. A., Aboulhosn, J., Connolly, H. M., Khanna, A., Koos, B. J., ... & Stout, K. (2017). Management of pregnancy in patients with complex congenital heart disease: a scientific statement for healthcare professionals from the American Heart Association. Circulation, 135(8), e50-e87.
https://doi.org/10.1161/CIR.0000000000000458
Coffey, S., Roberts-Thomson, R., Brown, A., Carapetis, J., Chen, M., Enriquez-Sarano, M., ... & Prendergast, B. D. (2021). Global epidemiology of valvular heart disease. Nature Reviews Cardiology, 18(12), 853-864. https://doi.org/10.1038/s41569-021-00570-z
Davutoğlu, E., Yüksel, M. A., Öncül, M., Şükrü, Ç. E. B. İ., & Madazlı, R. (2015). Kalp hastalığı ve gebelik: Maternal ve fetal sonuçlar. Journal Of Clinical Obstetrics & Gynecology, 25(2), 103-110. https://doi.org/10.5336/gynobstet.2014-43155
Drenthen, W., Pieper, P. G., Roos-Hesselink, J. W., van Lottum, W. A., Voors, A. A., Mulder, B. J., ... & Zahara Investigators. (2007). Outcome of pregnancy in women with congenital heart disease: a literature review. Journal of the American College of Cardiology, 49(24), 2303-2311. https://doi.org/10.1016/j.jacc.2007.03.027
Ducas, R. A., Javier, D. A., D’Souza, R., Silversides, C. K., & Tsang, W. (2020). Pregnancy outcomes in women with significant valve disease: A systematic review and meta-analysis. Heart, 106(7), 512-519. https://doi.org/10.1136/heartjnl-2019-315859
Eggleton, E. J., Bhagra, C. J., Patient, C. J., Belham, M., Pickett, J., & Aiken, C. E. (2023). Maternal left ventricular function and adverse neonatal outcomes in women with cardiac disease. Archives of Gynecology and Obstetrics, 307(5), 1431-1439. https://doi.org/10.1007/s00404-022-06635-9
Eggleton, E. J., Mcmurrugh, K. J., & Aiken, C. E. (2022). Perinatal outcomes in pregnancies complicated by maternal cardiomyopathy: A systematic review and meta-analysis. American Journal of Obstetrics and Gynecology, 228(3), 283-291. https://doi.org/10.1016/j.ajog.2022.09.025
Giussani, D. A. (2021). Breath of life: Heart disease link to developmental hypoxia. Circulation, 144(17), 1429-1443. https://doi.org/10.1161/CIRCULATIONAHA.121.054689
Halpern, D. G., Weinberg, C. R., Pinnelas, R., Mehta-Lee, S., Economy, K. E., & Valente, A. M. (2019). Use of medication for cardiovascular disease during pregnancy: JACC state-of-the-art review. Journal of the American College of Cardiology, 73(4), 457-476. https://doi.org/10.1016/j.jacc.2018.10.075
Hardee, I., Wright, L., McCracken, C., Lawson, E., & Oster, M. E. (2021). Maternal and neonatal outcomes of pregnancies in women with congenital heart disease: a meta‐analysis. Journal of the American Heart Association, 10(8), e017834. https://doi.org/10.1161/JAHA.120.017834
Hilfiker-Kleiner, D., Haghikia, A., Nonhoff, J., & Bauersachs, J. (2015). Peripartum cardiomyopathy: current management and future perspectives. European Heart Journal, 36(18), 1090-1097. https://doi.org/10.1093/eurheartj/ehv009
https://data.unicef.org/topic/maternal-health/maternal-mortality/ Accessed 26 June 2024
https://www.who.int/news-room/fact-sheets/detail/cardiovascular-diseases-(cvds) Accessed 05 July 2024
Kılıç, A., Çalım, S.İ. (2020). Kardiyovasküler Bozukluklar ve Gebelik. (Ed. Emel Taşçı Turan ve Emine Gerçek). Yüksek Riskli gebelikler ve Yönetimi. Nobel Akademik Yayıncılık. s.351-352.
Kızılırmak, A., Nacar, G., & Timur Taşhan, S. (2022). Doğum, Kadın Sağlığı ve Hastalıkları Hemşireliği. İçinde
N.Evşen (Ed.), Gebeliği etkileyen sağlık durumları. (s.272). Akademisyen Kitabevi. https://doi.org/10.37609/akya.1183
Kotit, S., & Yacoub, M. (2021). Cardiovascular adverse events in pregnancy: A global perspective. Global Cardiology Science & Practice, 2021(1). https://doi.org/10.21542/gcsp.2021.5
Koutrolou-Sotiropoulou, P., Parikh, P. B., Miller, C., Lima, F. V., Butler, J., & Stergiopoulos, K. (2015). Impact of heart disease on maternal and fetal outcomes in pregnant women. The American Journal of Cardiology, 116(3), 474-480. https://doi.org/10.1016/j.amjcard.2015.04.063
Lewey, J., Andrade, L., & Levine, L. D. (2021). Valvular heart disease in pregnancy. Cardiology Clinics, 39(1), 151-161. https://doi.org/10.1016/j.ccl.2020.09.010.
Lima, F. V., Yang, J., Xu, J., & Stergiopoulos, K. (2017). National trends and in-hospital outcomes in pregnant women with heart disease in the United States. The American Journal of Cardiology, 119(10), 1694-1700. https://doi.org/10.1016/j.amjcard.2017.02.003
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Nguyen Manh, T., Bui Van, N., Le Thi, H., Vo Hoang, L., Nguyen Si Anh, H., Trinh Thi Thu, H., Nguyen Xuan, T., et al. (2019). Pregnancy with Heart Disease: Maternal Outcomes and Risk Factors for Fetal Growth Restriction. International Journal of Environmental Research and Public Health, 16(12), 2075. https://doi.org/10.3390/ijerph16122075
Owens, A., Yang, J., Nie, L., Lima, F., Avila, C., & Stergiopoulos, K. (2018). Neonatal and maternal outcomes in pregnant women with cardiac disease. Journal of the American Heart Association, 7(21), e009395. https://doi.org/10.1161/JAHA.118.009395
Parikh, N. I., Gonzalez, J. M., Anderson, C. A., Judd, S. E., Rexrode, K. M., Hlatky, M. A., ... & American Heart Association Council on Epidemiology and Prevention; Council on Arteriosclerosis, Thrombosis and Vascular Biology; Council on Cardiovascular and Stroke Nursing; and the Stroke Council. (2021). Adverse pregnancy outcomes and cardiovascular disease risk: unique opportunities for cardiovascular disease prevention in women: a scientific statement from the American Heart Association. Circulation, 143(18), e902-e916. https://doi.org/10.1161/CIR.0000000000000961
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Pregnancy, Childbirth, and Postpartum Period in Cardiovascular Diseases
Year 2024,
Volume: 9 Issue: 3, 385 - 392, 31.12.2024
Cardiovascular diseases during pregnancy are the primary cause of indirect maternal deaths. Factors such as advancing maternal age, obesity, sedentary lifestyle, and changing dietary habits contribute to the increased maternal mortality rates associated with cardiovascular diseases. Comprehensive history taking and physical examination should be conducted during pregnancy to assess cardiovascular risk. Accordingly, the pregnancy and delivery should be planned based on the classification of the mother's heart disease and any identified cardiac conditions. Women with heart disease must deliver in a hospital setting. The mode and place of delivery should be determined by an experienced healthcare team. Delivery should occur in a center where a multidisciplinary approach can be implemented. While an individualized birth plan should be developed, vaginal delivery is generally preferred. Medications used by the woman should be evaluated for safety during the postpartum and lactation periods. This review aims to examine cardiovascular diseases during pregnancy, delivery, and the postpartum period in light of the literature.
ACOG Practice Bulletin No. 212 (2019): Pregnancy and heart disease. Obstetrics & Gynecology, 133(5), e320-e356. https://doi.org/10.1097/AOG.0000000000003243
Balci, A., Sollie-Szarynska, K. M., van der Bijl, A. G., Ruys, T. P., Mulder, B. J., Roos-Hesselink, J. W., ... & Pieper, P. G. (2014). Prospective validation and assessment of cardiovascular and offspring risk models for pregnant women with congenital heart disease. Heart, 100(17), 1373-1381. https://doi.org/10.1136/heartjnl-2014-305597
Beaton, A., Okello, E., Scheel, A., DeWyer, A., Ssembatya, R., Baaka, O., ... & Sable, C. (2019). Impact of heart disease on maternal, fetal and neonatal outcomes in a low-resource setting. Heart, 105(10), 755-760. https://doi.org/10.1136/heartjnl-2018-313810
Bennett, J. A., Riegel, B., Bittner, V., & Nichols, J. (2002). Validity and reliability of the NYHA classes for measuring research outcomes in patients with cardiac disease. Heart & Lung, 31(4), 262-270. https://doi.org/10.1067/mhl.2002.124554
Bredy, C., Deville, F., Huguet, H., Picot, M. C., De La Villeon, G., Abassi, H., ... & Amedro, P. (2023). Which risk score best predicts cardiovascular outcome in pregnant women with congenital heart disease?. European Heart Journal-Quality of Care and Clinical Outcomes, 9(2), 177-183. https://doi.org/10.1093/ehjqcco/qcac019
Bright, R. A., Lima, F. V., Avila, C., Butler, J., & Stergiopoulos, K. (2021). Maternal Heart Failure. Journal of the American Heart Association, 10(14), e021019. https://doi.org/10.1161/JAHA.121.021019
Canobbio, M. M., Warnes, C. A., Aboulhosn, J., Connolly, H. M., Khanna, A., Koos, B. J., ... & Stout, K. (2017). Management of pregnancy in patients with complex congenital heart disease: a scientific statement for healthcare professionals from the American Heart Association. Circulation, 135(8), e50-e87.
https://doi.org/10.1161/CIR.0000000000000458
Coffey, S., Roberts-Thomson, R., Brown, A., Carapetis, J., Chen, M., Enriquez-Sarano, M., ... & Prendergast, B. D. (2021). Global epidemiology of valvular heart disease. Nature Reviews Cardiology, 18(12), 853-864. https://doi.org/10.1038/s41569-021-00570-z
Davutoğlu, E., Yüksel, M. A., Öncül, M., Şükrü, Ç. E. B. İ., & Madazlı, R. (2015). Kalp hastalığı ve gebelik: Maternal ve fetal sonuçlar. Journal Of Clinical Obstetrics & Gynecology, 25(2), 103-110. https://doi.org/10.5336/gynobstet.2014-43155
Drenthen, W., Pieper, P. G., Roos-Hesselink, J. W., van Lottum, W. A., Voors, A. A., Mulder, B. J., ... & Zahara Investigators. (2007). Outcome of pregnancy in women with congenital heart disease: a literature review. Journal of the American College of Cardiology, 49(24), 2303-2311. https://doi.org/10.1016/j.jacc.2007.03.027
Ducas, R. A., Javier, D. A., D’Souza, R., Silversides, C. K., & Tsang, W. (2020). Pregnancy outcomes in women with significant valve disease: A systematic review and meta-analysis. Heart, 106(7), 512-519. https://doi.org/10.1136/heartjnl-2019-315859
Eggleton, E. J., Bhagra, C. J., Patient, C. J., Belham, M., Pickett, J., & Aiken, C. E. (2023). Maternal left ventricular function and adverse neonatal outcomes in women with cardiac disease. Archives of Gynecology and Obstetrics, 307(5), 1431-1439. https://doi.org/10.1007/s00404-022-06635-9
Eggleton, E. J., Mcmurrugh, K. J., & Aiken, C. E. (2022). Perinatal outcomes in pregnancies complicated by maternal cardiomyopathy: A systematic review and meta-analysis. American Journal of Obstetrics and Gynecology, 228(3), 283-291. https://doi.org/10.1016/j.ajog.2022.09.025
Giussani, D. A. (2021). Breath of life: Heart disease link to developmental hypoxia. Circulation, 144(17), 1429-1443. https://doi.org/10.1161/CIRCULATIONAHA.121.054689
Halpern, D. G., Weinberg, C. R., Pinnelas, R., Mehta-Lee, S., Economy, K. E., & Valente, A. M. (2019). Use of medication for cardiovascular disease during pregnancy: JACC state-of-the-art review. Journal of the American College of Cardiology, 73(4), 457-476. https://doi.org/10.1016/j.jacc.2018.10.075
Hardee, I., Wright, L., McCracken, C., Lawson, E., & Oster, M. E. (2021). Maternal and neonatal outcomes of pregnancies in women with congenital heart disease: a meta‐analysis. Journal of the American Heart Association, 10(8), e017834. https://doi.org/10.1161/JAHA.120.017834
Hilfiker-Kleiner, D., Haghikia, A., Nonhoff, J., & Bauersachs, J. (2015). Peripartum cardiomyopathy: current management and future perspectives. European Heart Journal, 36(18), 1090-1097. https://doi.org/10.1093/eurheartj/ehv009
https://data.unicef.org/topic/maternal-health/maternal-mortality/ Accessed 26 June 2024
https://www.who.int/news-room/fact-sheets/detail/cardiovascular-diseases-(cvds) Accessed 05 July 2024
Kılıç, A., Çalım, S.İ. (2020). Kardiyovasküler Bozukluklar ve Gebelik. (Ed. Emel Taşçı Turan ve Emine Gerçek). Yüksek Riskli gebelikler ve Yönetimi. Nobel Akademik Yayıncılık. s.351-352.
Kızılırmak, A., Nacar, G., & Timur Taşhan, S. (2022). Doğum, Kadın Sağlığı ve Hastalıkları Hemşireliği. İçinde
N.Evşen (Ed.), Gebeliği etkileyen sağlık durumları. (s.272). Akademisyen Kitabevi. https://doi.org/10.37609/akya.1183
Kotit, S., & Yacoub, M. (2021). Cardiovascular adverse events in pregnancy: A global perspective. Global Cardiology Science & Practice, 2021(1). https://doi.org/10.21542/gcsp.2021.5
Koutrolou-Sotiropoulou, P., Parikh, P. B., Miller, C., Lima, F. V., Butler, J., & Stergiopoulos, K. (2015). Impact of heart disease on maternal and fetal outcomes in pregnant women. The American Journal of Cardiology, 116(3), 474-480. https://doi.org/10.1016/j.amjcard.2015.04.063
Lewey, J., Andrade, L., & Levine, L. D. (2021). Valvular heart disease in pregnancy. Cardiology Clinics, 39(1), 151-161. https://doi.org/10.1016/j.ccl.2020.09.010.
Lima, F. V., Yang, J., Xu, J., & Stergiopoulos, K. (2017). National trends and in-hospital outcomes in pregnant women with heart disease in the United States. The American Journal of Cardiology, 119(10), 1694-1700. https://doi.org/10.1016/j.amjcard.2017.02.003
Madazlı, R. (2021). Gebelik ve Sistemik Hastalıklar. İçinde Rıza Madazlı (Ed.) Kalp Hastalıkları. (s. 6). İstanbul Tıp Kitabevleri.
McKenna, W. J., Maron, B. J., & Thiene, G. (2017). Classification, epidemiology, and global burden of cardiomyopathies. Circulation Research, 121(7), 722-730. https://doi.org/10.1161/CIRCRESAHA.117.309711
Mehta, L. S., Warnes, C. A., Bradley, E., Burton, T., Economy, K., Mehran, R., ... & American Heart Association Council on Clinical Cardiology; Council on Arteriosclerosis, Thrombosis and Vascular Biology; Council on Cardiovascular and Stroke Nursing; and Stroke Council. (2020). Cardiovascular considerations in caring for pregnant patients: a scientific statement from the American Heart Association. Circulation, 141(23), e884-e903. https://doi.org/10.1161/CIR.0000000000000772
Nguyen Manh, T., Bui Van, N., Le Thi, H., Vo Hoang, L., Nguyen Si Anh, H., Trinh Thi Thu, H., Nguyen Xuan, T., et al. (2019). Pregnancy with Heart Disease: Maternal Outcomes and Risk Factors for Fetal Growth Restriction. International Journal of Environmental Research and Public Health, 16(12), 2075. https://doi.org/10.3390/ijerph16122075
Owens, A., Yang, J., Nie, L., Lima, F., Avila, C., & Stergiopoulos, K. (2018). Neonatal and maternal outcomes in pregnant women with cardiac disease. Journal of the American Heart Association, 7(21), e009395. https://doi.org/10.1161/JAHA.118.009395
Parikh, N. I., Gonzalez, J. M., Anderson, C. A., Judd, S. E., Rexrode, K. M., Hlatky, M. A., ... & American Heart Association Council on Epidemiology and Prevention; Council on Arteriosclerosis, Thrombosis and Vascular Biology; Council on Cardiovascular and Stroke Nursing; and the Stroke Council. (2021). Adverse pregnancy outcomes and cardiovascular disease risk: unique opportunities for cardiovascular disease prevention in women: a scientific statement from the American Heart Association. Circulation, 143(18), e902-e916. https://doi.org/10.1161/CIR.0000000000000961
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The Journal of Sivas Cumhuriyet University Institute of Health Sciences is an international, peer-reviewed scientific journal published by Sivas Cumhuriyet University, Institute of Health Sciences.